非药物戒烟效果的网状Meta分析  

Efficacy of non-pharmacotherapy for smoking cessation:a network meta-analysis

作　　者：郭康乐 周丽营 杨超群 商雪 鄂芬芬 徐梦 吴亚楠 杨克虎[1,2,3] 李秀霞 GUO Kangle;ZHOU Liying;YANG Chaoqun;SHANG Xue;E Fenfen;XU Meng;WU Yanan;YANG Kehu;LI Xiuxia(Health Technology Assessment Center/Evidence-Based Social Science Research Center,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Evidence Based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province,Lanzhou 730000,P.R.China)

机构地区：[1]兰州大学循证社会科学研究中心/卫生技术评价中心,兰州大学公共卫生学院,兰州730000 [2]兰州大学循证医学中心,兰州大学基础医学院,兰州730000 [3]甘肃省循证医学与知识翻译重点实验室,兰州730000

出　　处：《中国循证医学杂志》2022年第11期1256-1264,共9页Chinese Journal of Evidence-based Medicine

基　　金：国家自然科学基金项目(编号:72074103)。

摘　　要：目的系统评价不同非药物戒烟方式的戒烟效果。方法计算机检索PubMed、EMbase、The Cochrane Library、Web of Science、CBM、WanFang Data、VIP和CNKI数据库,搜集关于非药物戒烟的随机对照试验(RCT),检索时限均从建库至2021年11月。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 15.1软件进行网状Meta分析。结果共纳入27个RCT,包括14种非药物干预方式。网状Meta分析结果显示,与常规建议相比,视频咨询[OR=2.34,95%CI(1.32,4.15)]、手机短信[OR=1.82,95%CI(1.03,3.20)]、动机性访谈[OR=2.00,95%CI(1.11,3.59)]和健康教育[OR=3.40,95%CI(1.52,7.57)]的7天时点戒烟率更高(P<0.05)。排序结果显示健康教育成为最佳干预的可能性最大(86.20%),其次为视频咨询(74.11%)。结论现有证据显示,健康教育、视频咨询、电话咨询、手机短信和动机性访谈等干预方式均具有较好的短期戒烟效果,其中健康教育可能最优。受纳入研究数量和质量的限制,上述结论尚待更多高质量研究予以验证。Objective To systematically review the efficacy of different non-pharmacological interventions for smoking cessation.Methods PubMed,EMbase,The Cochrane Library,Web of Science,CBM,WanFang Data,VIP and CNKI databases were electronically searched to collect randomized controlled trials(RCTs)of different nonpharmacological interventions for smoking cessation from inception to November,2021.Two reviewers independently screened literature,extracted data and assessed the risk of bias of included studies;then,network meta-analysis was performed by using Stata 15.1 software.Results A total of 27 RCTs involving 14 interventions were included.The results of the network meta-analysis showed that compared with conventional advice,video counseling(OR=2.34,95%CI 1.32 to4.15),mobile phone text message(OR=1.82,95%CI 1.03 to 3.20),motivational interview(OR=2.00,95%CI 1.11 to 3.59)and health education(OR=3.40,95%CI 1.52 to 7.57)were higher in quitting rate(P<0.05).The sort results showed that health education was the most likely to be the best intervention(86.20%),followed by video consultation(74.10%).Conclusion Current evidence shows that the smoking cessation effects of health education,video counseling,telephone counseling,mobile phone text message and motivational interview.Among them,health education may be the best.Due to the limited quality and quantity of the included studies,more high-quality studies are needed to verify the above conclusion.

关 键 词：非药物干预 戒烟 系统评价 网状Meta分析 随机对照试验 

分 类 号：R163[医药卫生—公共卫生与预防医学]