2015—2017年江苏六地区35~75岁居民乳类及制品摄入与心血管病高危风险关联  

Relationship between dairy and product consumption and the high-risk of cardiovascular diseases of 35-75 years old residents in 6 districts of Jiangsu Province from 2015 to 2017

作　　者：吴叶[1] 盛红艳[1] 戴宁彬 顾亦斌 张宁[1] 崔岚[3] 苏健[3] 覃玉[3] 周金意[3] Wu Ye;Sheng Hongyan;Dai Ningbin;Gu Yibin;Zhang Ning;Cui Lan;Su Jian;Qin Yu;Zhou Jinyi(Changshu Municipal Center for Disease Control and Prevention,Suzhou 215500,China;Suzhou Center for Disease Control and Prevention,Suzhou 215004,China;Jiangsu Province Center for Disease Control and Prevention,Nanjing 210009,China)

机构地区：[1]常熟市疾病预防控制中心,苏州215500 [2]苏州市疾病预防控制中心,苏州215004 [3]江苏省疾病预防控制中心,南京210009

出　　处：《卫生研究》2022年第6期975-980,共6页Journal of Hygiene Research

基　　金：国家重大公共卫生项目(No.csws201815)。

摘　　要：目的 了解乳类及制品摄入对心血管病高危风险的影响。方法 于2015年6月至2017年9月,用整群抽样方法对江苏省6个地区35~75周岁居民进行心血管病高危人群早期筛查,经心血管病患病风险评估,40 234人被列为心血管病高危研究对象,年龄(57.30±9.44)岁,女性24 608人(61.15%),农村20 412人(50.72%),进行问卷调查、体格检查、实验室检测,再经倾向性得分匹配,最终纳入35 104名对象。结果 研究对象乳类及制品摄入频率<1 d/周者达23 607人(67.30%)。以乳类及制品摄入<1 d/周组为参照,调整城乡、文化程度、职业、家庭年收入、饮酒、体质指数、腹型肥胖及蔬菜、水果摄入,多因素Logistic回归分析显示,随着乳类及制品摄入频率增加,心血管病高危风险呈下降趋势(P<0.001),其中以乳类及制品频率4~6 d/周组风险最低(OR=0.608,95%CI 0.546~0.677)。相加交互分析发现,联合蔬菜摄入显著降低心血管病高危风险(P<0.05),在相同乳类及制品摄入频率下,水果摄入频率增加可降低心血管高危风险。结论 较多乳类及制品摄入有助于降低心血管病高危风险,联合蔬菜、水果摄入能协同降低心血管高危,蔬菜作用强于水果。OBJECTIVE To explore the effect of intake of milk and milk products on high risk of cardiovascular disease.METHODS Six districts in Jiangsu Province were selected as project sites by using cluster sampling method. The residents aged 35-75 years old in the districts were screened at early stage for high risk population of cardiovascular diseases from June 2015 to September 2017, and the risk of cardiovascular diseases was assessed, a total of 40 234 subjects were classified as high-risk subjects of cardiovascular disease((57.30±9.44) years old, 24 608 female(61.15%), 20 412 rural residents(50.72%)). Through questionnaire, physical examination, laboratory test, and propensity score matching, 35 104 subjects were finally included in this study. The t test, χ~2 test, multivariate Logistic regression and additive interaction analysis were used to analyze the data with software of SPSS 23.0.RESULTS There were 67.30%(n=23 607) of subjects with milk and product consumption<1 d/week. With the frequency as a reference, adjusted urban and rural areas, educational level, occupation, annual family income, drinking, BMI, abdominal obesity, and intake of vegetables and fruits, multiple Logistic regression analysis showed that the risk of cardiovascular disease decreased with the increase of intake frequency of milk and milk products(P<0.001), the frequency of 4-6 d/week was the lowest(OR=0.608,95% CI 0.546-0.677). Additive interaction analysis found that combination with vegetable consumption significantly reduced the high risk of cardiovascular diseases(P<0.05). While the high risk of cardiovascular disease was reduced by increasing fruit intake frequency at the same intake frequency of milk and products.CONCLUSION More intake milk and product can reduce the high-risk of cardiovascular diseases. Combination with vegetables or fruits could synergistically reduce the high risk, the effect is stronger with vegetables than that with fruits.

关 键 词：乳类及制品 摄入量 心血管疾病风险 敏感性分析 关联分析 

分 类 号：R181.37[医药卫生—流行病学] R151.41[医药卫生—公共卫生与预防医学]