不同鼻饲置管方式对早产儿经口喂养的临床研究  

Clinical Study on Oral Feeding of Premature Infants by Different Nasal Feeding Tube Placement Methods

作　　者：颜惠萍[1] 陈小玲[1] 张美莉[1] YAN Huiping;CHEN Xiaoling;ZHANG Meili(Newborn Intensive Care Unit,Quanzhou Children's Hospital,Quanzhou 362000,China)

机构地区：[1]泉州市儿童医院新生儿重症监护室,福建泉州362000

出　　处：《中国医药指南》2023年第3期45-48,共4页Guide of China Medicine

摘　　要：目的 探讨早产儿采取不同鼻饲置管方式喂养对其成长、营养状态、肠道菌群的影响。方法 选择2021年6月至2022年6月在我院出生的早产儿99例作为研究对象,根据鼻饲置管的不同方式分作A、B、C3组,A组早产儿采取间歇鼻饲注入喂养方式;B组早产儿采取持续鼻饲输注喂养方式,C组早产儿采取间歇持续鼻饲输注喂养方式,分别记录3组早产儿成长情况,同时检测3组早产儿喂养前后营养状态及肠道菌群变化,观察3组早产儿喂养耐受情况。结果 3组早产儿住院时间组间比较无统计学差异(P>0.05),C组早产儿体质量正常时间、完全肠道内喂养时间、黄疸持续时间均明显短于A组与B组早产儿(P<0.05)。3组早产儿喂养前经检测,营养状态、肠道菌群测定结果对比无统计学差异(P>0.05),喂养4周后,C组早产儿营养指标测定结果均高于A、B两组早产儿,同时肠道菌群双歧杆菌、乳酸菌测定结果高于A、B两组早产儿(P<0.05)。C组早产儿出现喂养不耐受总发生率低于其他两组早产儿(P<0.05)。结论 早产儿接受鼻饲置管喂养时,可首选间歇持续注入喂养方式,相比单纯间歇或单纯持续喂养早产儿耐受性更加,促进营养吸收及早产儿成长,值得运用推广。Objective To investigate the effects of different nasal feeding methods on the growth, nutritional status and intestinal flora of premature infants. Methods All 99 premature infants born in our hospital from June 2021 to June 2022 were selected as the study subjects. According to the different ways of nasal feeding tube placement, they were divided into three groups: A, B and C. Group A premature infants were fed with intermittent nasal feeding;The preterm infants in group B were fed by continuous nasal feeding and infusion, while the preterm infants in group C were fed by intermittent continuous nasal feeding and infusion. The growth of the three groups of preterm infants were recorded respectively.At the same time, the nutritional status and intestinal flora changes of the three groups of preterm infants before and after feeding were detected,and the feeding tolerance of the three groups of preterm infants was observed. Results There was no significant difference in hospitalization time among the three groups(P>0.05). The normal weight time, complete enteral feeding time and jaundice duration of premature infants in group C were significantly shorter than those in group A and group B(P<0.05). There was no significant difference in nutritional status and intestinal flora test results among the three groups of preterm infants before feeding(P>0.05). After 4 weeks of feeding, the nutritional index test results of group C preterm infants were higher than those of group A and group B preterm infants, and the intestinal flora bifidobacteria and lactic acid bacteria test results were higher than those of group A and group B preterm infants(P<0.05). The total incidence of feeding intolerance in group C was lower than that in the other two groups(P<0.05). Conclusion When preterm infants receive nasal feeding and tube feeding, intermittent continuous feeding can be the first choice. Compared with simple intermittent or simple continuous feeding, preterm infants are more tolerant, promote nutrition absorption and growth o

关 键 词：不同鼻饲置管方式 早产儿 营养状态 肠道菌群 

分 类 号：R72[医药卫生—儿科]