肺炎支原体感染和小儿哮喘之间的相关性  

Association Between Mycoplasma Pneumoniae Infection and Childhood Asthma

作　　者：宋亚尧 SONG Yayao(Department of Paediatrics,Beipiao Hospital of Traditional Chinese Medicine,Beipiao 122100,China)

机构地区：[1]北票市中医院儿科,辽宁北票122100

出　　处：《中国医药指南》2023年第3期65-68,共4页Guide of China Medicine

摘　　要：目的 评价肺炎支原体感染和小儿哮喘之间的相关性。方法 选择2019年1月至2019年12月到我院进行治疗的25例合并肺炎支原体感染的小儿哮喘患儿作为观察组,另外选择同期来我院进行治疗的未合并肺炎支原体感染的25例小儿哮喘患儿作为对照组,对所有患儿的临床资料进行统计和回顾性分析,统计观察组中重症感染和轻症感染的例数,并且对所有调查对象进行总IgE和TNF-α检验,对检验结果进行分析比较。结果 观察组中存在重症肺炎支原体感染11例,轻症肺炎支原体感染14例;观察组患儿的总IgE和TNF-α水平明显比对照组更高,差异有统计学意义(P<0.05);观察组中重症感染患儿的总IgE和TNF-α相关水平明显高于轻症感染,差异有统计学意义(P<0.05);观察组的睡眠质量明显比对照组更差,差异有统计学意义(P<0.05);观察组的舒适度明显比对照组更差,差异有统计学意义(P<0.05);观察组(22例,占88.00%)患儿对治疗的依从性比对照组(16例,占64.00%)更高,差异有统计学意义(P<0.05)。结论 在临床上肺炎支原体感染会诱发小儿哮喘,其是小儿哮喘发作的一个主要因素,二者之间的关系明显,肺炎支原体感染越严重则小儿哮喘的病症也就越重,且患儿的睡眠质量、舒适度明显更差,治疗难度更大,故临床应采取积极的治疗措施对此进行重视。Objective To evaluate the correlation between mycoplasma pneumoniae infection and childhood asthma. Methods The period from January 2019 to December 2019 was selected as the investigation time of this article, and 25 children with asthma complicated by mycoplasma pneumoniae infection who were treated in our hospital during this period were selected as the observation group of this article. The 25 children with asthma who were treated without mycoplasma pneumoniae infection were taken as the control group. The clinical data of all the children were statistically and retrospectively analyzed, and the number of severe and mild infections in the observation group was counted. The subjects were tested for total IgE and TNF-α, and the test results were analyzed and compared.Results There were 11 cases of severe mycoplasma pneumoniae infection and 14 cases of mild mycoplasma pneumoniae infection in the observation group. The IgE and TNF-α levels in the observation group were significantly higher than those in the control group, with statistical difference(P<0.05). The IgE and TNF-α correlation level of severe infection in the observation group was significantly higher than that of mild infection, with statistical difference(P<0.05). The sleep quality of observation group was significantly worse than that of control group, with statistical difference(P<0.05). The comfort level of the observation group was significantly worse than that of the control group, with statistical difference(P<0.05). The compliance of the observation group(22 cases, accounting for 88.00%) to the treatment was higher than that of the control group(16 cases, accounting for 64.00%) was higher, with statistical significance(P<0.05).Conclusion Mycoplasma pneumoniae infection can induce the onset of asthma in children, and it can be regarded as a major factor in childhood asthma attacks in kindergarten teachers. The relationship between the two is obvious. Moreover, the sleep quality and comfort of children are significantly worse, and the treatmen

关 键 词：肺炎支原体感染 小儿哮喘 舒适度 睡眠质量 生活质量 依从性 

分 类 号：R256.12[医药卫生—中医内科学]