Octopaminergic neurons function in appetitive but not aversive olfactory learning and memory in Bactrocera dorsalis  

作　　者：Jin-Xin Yu Qian Xiang Jia-Bao Qu Yan-Min Hui Tao Lin Xin-Nian Zeng Jia-Li Liu 

机构地区：[1]Guangdong Engineering Research Center for Insect Behavior Regulation,College of Plant Protection,South China Agricultural University,Guangzhou,Guangdong,China [2]College of Life Sciences,Department of Biological Science,Shangrao Normal University,Shangrao,Jiangxi,China

出　　处：《Insect Science》2022年第6期1747-1760,共14页昆虫科学（英文版）

基　　金：funded by the National Natural Science Foundation of China(32072486,31971424,and 31572314).

摘　　要：The biogenic amine octopamine(OA,invertebrate counterpart of nora-drenaline)plays critical roles in the regulation of olfactory behavior.Historically,OA has been thought to mediate appetitive but not aversive learning in honeybees,fruit flies(Drosophila),and crickets.However,this viewpoint has recently been challenged because OA activity through aβ-adrenergic-like receptor drives both appetitive and aversive learn-ing.Here,we explored the roles of OA neurons in olfactory learning and memory retrieval in Bactrocera dorsalis.We trained flies to associate an orange odor with a sucrose reward or to associate methyl eugenol,a male lure,with N,N-diethyl-3-methyl benzoyl amide(DEET)punishment.We then treated flies with OA receptor antagonists before appetitive or aversive conditioning and a memory retention test.Injection of OA receptor antagonist mianserin or epinastine into the abdomen of flies led to impaired of appetitive learning and memory retention with a sucrose reward,while aversive learning and memory reten-tion with DEET punishment remained intact.Our results suggest that the OA signaling participates in appetitive but not aversive learning and memory retrieval in B.dorsalis through OA receptors.

关 键 词：APPETITIVE aversive Bactrocera dorsalis learning and memory OCTOPAMINE 

分 类 号：Q96[生物学—昆虫学]