Innovations and stepwise evolution of CBFs/DREB1s and their regulatory networks in angiosperms  

作　　者：Yuqi Nie Liangyu Guo Fuqiang Cui Yirong Shen Xiaoxue Ye Deyin Deng Shuo Wang Jianhua Zhu Wenwu Wu 

机构地区：[1]State Key Laboratory of Subtropical Silviculture,School of Forestry and Biotechnology,Zhejiang A&F University,Hangzhou 311300,China [2]Institute of Tropical Biosciences and Biotechnology,Chinese Academy of Tropical Agricultural Sciences,Haikou 571101,China [3]School of Life Sciences,Anhui Agricultural University,Hefei 230036,China [4]Department of Plant Science and Landscape Architecture,University of Maryland,College Park,Maryland 20742,USA

出　　处：《Journal of Integrative Plant Biology》2022年第11期2111-2125,共15页植物学报（英文版）

基　　金：supported by National Key R&D Program of China(2018YFD1000604);National Natural Science Foundation of China(31871233);Natural Science Foundation of Zhejiang Province(LY22C160005)。

摘　　要：The C-repeat binding factors/dehydrationresponsive element binding protein 1 s(CBFs/DREB1 s)have been identified as major regulators of cold acclimation in many angiosperm plants.However,their origin and evolutionary process associated to cold responsiveness are still lacking.By integrating multi-omics data of genomes,transcriptomes,and CBFs/DREB1 s genome-wide binding profiles,we unveil the origin and evolution of CBFs/DREB1 s and their regulatory network.Gene collinearity and phylogeny analyses show that CBF/DREB1 is an innovation evolved from tandem duplication-derived DREBⅢgene.A subsequent event of e-whole genome duplication led to two CBF/DREB1 archetypes(CladesⅠandⅡ)in ancient angiosperms.In contrast to cold-insensitivity of Clade I and their parent DREBⅢgenes,CladeⅡevolved a further innovation in cold-sensitive response and was stepwise expanded in eudicots and monocots by independent duplications.In geological time,the duplication events were mainly enriched around the Cretaceous-Paleogene(K-Pg)boundary and/or in the Late Cenozoic Ice Age,when the global average temperature significantly decreased.Consequently,the duplicated CBF/DREB1 genes contributed to the rewiring of CBFs/DREB1 s-regulatory network for cold tolerance.Altogether,our results highlight an origin and convergent evolution of CBFs/DREB1 s and their regulatory network probably for angiosperms adaptation to global cooling.

关 键 词：CBF/DREB1 cold acclimation global cooling ice age K-Pg boundary PALEOTEMPERATURE tandem duplication(TD) whole genome duplication(WGD) 

分 类 号：Q943[生物学—植物学]