穴位贴敷对骨质疏松症患者干预效果的Meta分析  

A meta-analysis of the effect of acupoint application on osteoporosis

作　　者：龚桃林 云洁[2] 陈艺曦 袁雷 GONG Taolin

机构地区：[1]成都中医药大学,四川成都610072 [2]成都中医药大学附属医院,四川成都610072

出　　处：《中医临床研究》2022年第31期115-119,共5页Clinical Journal Of Chinese Medicine

摘　　要：目的:系统评价穴位贴敷对骨质疏松症患者干预效果的有效性。方法:检索PubMed、Embase、Cochrane、知网、万方、维普、中国生物医学文献数据库等国内外共7个数据库,检索时间从建库至2021年12月,纳入有关穴位贴敷治疗骨质疏松症的随机对照研究,采用RevMan 5.3软件进行Meta分析。结果:共纳入12项随机对照研究,包含1070例骨质疏松症患者。与对照组相比,穴位贴敷组在提高治疗总有效率、缓解骨质疏松性疼痛、改善患者骨密度、提高血清骨钙素水平等方面优于对照组,差异均有统计学意义(P<0.05);在血清Ⅰ型前胶原氨基端前肽(N-terminal Propeptide of TypeⅠProcollagen,PⅠNP)与尿胶原C末端肽(C-terminal Cross Linked Peptide,CTX)水平方面,两组患者无明显差别。结论:与西医常规治疗相比,穴位贴敷联合西药治疗骨质疏松症效果更优,但因纳入研究的质量及患者数量有限,尚需要更深入的研究加以证实。Objective:To systematically evaluate the effectiveness of acupoint application on osteoporosis Methods:In 7 databases including PubMed,Embase,Cochrane,CNKI,Wanfang,VIP and CBM,the randomized controlled studies on treating osteoporosis by acupoint application from database initial stage to December 2021 were retrieved and included,and a metaanalysis was performed by RevMan 5.3 software.Results:A total of 12 randomised controlled studies were included,with 1070 cases.The statistical results showed that the acupoint application group was superior to the control group in improving the total efficiency,relieving the pain,improving the bone mineral density,and increasing the level of serum osteocalcin,and the differences were all statistically significant(P<0.05).There was no significant difference in serum PINP and CTX between the two groups.Conclusion:Compared with conventional Western medicine,acupoint application plus Western medicine is more effective on osteoporosis.However,due to the limited quality of the included studies and small sample size,further studies are needed to confirm the result.

关 键 词：中医中药 穴位贴敷 骨质疏松症 META分析 

分 类 号：R245.9[医药卫生—针灸推拿学]