针灸推拿联合运脾汤对上呼吸道感染后脾虚综合征患儿肠道微生态、体格发育和血清微量元素及食欲调节因子的影响  

Effects of acupuncture and push combined with Yunpi Decoction on intestinal microecology,physical development and serum trace elements and appetite regulators in children with upper respiratory tract infection syndrome of spleen deficiency

作　　者：赵敏[1] 耿文婧 冯颖颖 李雪 ZHAO Min;GENG Wenjing;FENG Yingying;LI Xue(Department of Traditional Chinese Medicine,Shijiazhuang People’s Hospital,Shijiazhuang,050000,China)

机构地区：[1]石家庄市人民医院中医科,石家庄050000

出　　处：《中国中西医结合消化杂志》2022年第11期774-779,共6页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：河北省中医药科研计划(No:2022485);石家庄市科学技术研究与发展指导计划(No:171462213)。

摘　　要：目的:观察针灸推拿(针推)联合运脾汤对上呼吸道感染后脾虚综合征患儿肠道微生态、体格发育和血清微量元素及食欲调节因子的影响。方法:选择2021年2月—2022年2月收治的106例上呼吸道感染后脾虚综合征患儿为研究对象,用随机数字表法分组,每组各53例,对照组给予运脾汤治疗,观察组在对照组基础上给予针推治疗。治疗前、后检测两组患儿血清免疫球蛋白IgG、IgA、CD4^(+)T、CD8^(+)T细胞、锌、钙、铁、促人生长激素腺释放肽(ghrelin)、神经肽(NYP)、瘦素(leptin)、肠杆菌、双歧杆菌、乳酸杆菌含量,检测两组患儿胃窦部胃电图波形的反应面积、平均幅值、主频率,记录两组患儿平均身高及体重情况。结果:观察组患儿IgA、CD4^(+)T、IgG细胞含量较对照组高(P<0.05),CD8^(+)T细胞含量较对照组低(P<0.05);观察组ghrelin、NYP含量较对照组高(P<0.05),leptin含量较对照组低(P<0.05),钙、锌、铁含量较对照组高(P<0.05);观察组乳酸杆菌、双歧杆菌含量较对照组高(P<0.05),肠杆菌含量较对照组低(P<0.05);观察组胃窦部胃电图波形的反应面积、平均幅值、主频率高于对照组(P<0.05);观察组平均体重大于对照组(P<0.05),两组平均身高无明显变化(P>0.05)。观察组总有效率为96.23%,对照组总有效率为86.79%,观察组总有效率高于对照组(P<0.05)。结论:针推联合运脾汤治疗上呼吸道感染后脾虚综合征患儿,可提升患儿免疫功能,提高食欲调节因子及血清微量元素含量,调节机体肠道微生态,改善胃窦部胃电图指标,提升胃动力及临床疗效。Objective:To observe the effects of acupuncture and push combined with Yunpi Decoction on intestinal microecology,physical development,serum trace elements and appetite regulators in children with upper respiratory tract infection syndrome of spleen deficiency.Methods:A total of 106 children with syndrome of spleen deficiency after upper respiratory tract infection treated in the hospital from February 2021 to February 2022 were selected and divided into two groups according to the random number table method.Fifty-three patients were in the control group and given Yunpi decoction treatment,and 53 patients were in the observation group and given acupuncture therapy on the basis of the control group.Before and after treatment,the contents of serum immunoglobulin IgG,IgA,CD4^(+)T,CD8^(+)T cells,zinc,calcium,iron,ghrelin,NYP,leptin,Enterobacterium,bifidobacterium and Lactobacillus were detected.The response area,average amplitude and main frequency of the electrogastrogram waveform in the antrum of the two groups were detected,and the average height and weight of the two groups were recorded.Results:The contents of IgA,CD4^(+)T and IgG cells in the exploration group were higher than those in the reference group(P<0.05),the CD8^(+)T cells in the exploration group were lower than those in the reference group(P<0.05),and the contents of ghrelin and NYP in the exploration group were higher than those in the reference group(P<0.05),the content of leptin in the exploration group was lower than that in the reference group(P<0.05),the contents of calcium,zinc and iron in the exploration group were higher than those in the reference group(P<0.05),and the contents of Lactobacillus and Bifidobacterium in the exploration group were higher than those in the reference group(P<0.05),the content of Enterobacteriaceae in the exploration group was lower than that in the reference group(P<0.05),and the response area,average amplitude and main frequency of the electrogastric waveform of the gastric antrum in the exploration group were h

关 键 词：针灸 推拿 运脾汤 上呼吸道感染 脾虚综合征 儿童 免疫功能 食欲调节因子 血清微量元素 肠道微生态 体格发育 

分 类 号：R272[医药卫生—中医儿科学]