肥胖相关胰岛素抵抗的发病机制  

Pathogenesis of obesity related insulin resistance

作　　者：孟成 王翔宇[1,2] MENG Cheng;WANG Xiangyu(The Third Clinical Medical College of China Three Gorges University,Yichang,Hubei 443000,China;Department of Endocrinology,Gezhouba Central Hospital of Sinopharm,Yichang,Hubei 443002,China)

机构地区：[1]三峡大学第三临床医学院完,湖北宜昌443000 [2]国药葛洲坝中心医院内分泌科,湖北宜昌443002

出　　处：《医药前沿》2022年第28期27-29,共3页Journal of Frontiers of Medicine

摘　　要：肥胖可增加多种疾病的风险,如胰岛素抵抗(IR)、冠心病等。IR与多种代谢性疾病相关。目前,已有大量研究发现炎症反应、脂肪细胞因子等与IR密切相关。本文就肥胖相关IR的发病机制做一阐述。Obesity can increase the risk of many diseases,such as insulin resistance(IR),coronary heart disease,etc.IR is associated with many metabolic diseases.At present,a large number of studies have found that inflammation,adipocytokines and other factors are closely related to IR.This article will explain the pathogenesis of obesity related IR in order to guide clinical work.

关 键 词：肥胖 胰岛素抵抗 发病机制 脂肪细胞因子 炎症反应 

分 类 号：R587[医药卫生—内分泌]