妊娠期糖尿病与肠道菌群改变的研究进展  

Advances in the study on gestational diabetes mellitus and changes in intestinal flora

作　　者：曹雨之 王倩 孟昱君 廖佳玲(综述) 王英兰(审校)[1] CAO Yu-zhi;WANG Qian;MENG Yu-jun(Second Clinical Medical College of Jinan University,Shenzhen 518000,China)

机构地区：[1]暨南大学第二临床医学院,深圳518000

出　　处：《中国临床新医学》2022年第12期1192-1197,共6页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：深圳市科技计划项目(编号:JCYJ20190807144403563)。

摘　　要：妊娠期糖尿病(GDM)是妊娠常见并发症之一,表现为妊娠期糖代谢异常,对母儿造成长久的影响。妊娠期孕妇肠道菌群数量和种类出现生理性改变。研究表明,肠道菌群多样性及丰富度的改变是造成GDM发生发展的潜在因素。该文对GDM女性菌群改变的研究文献作一综述。Gestational diabetes mellitus(GDM)is one of the common complications of pregnancy,which manifests as abnormal glucose metabolism during pregnancy and causes profound effects on pregnant women and their fetuses.Physiological changes in the number and type of intestinal flora occur during pregnancy,and numerous studies have showed that changes in the diversity and abundance of intestinal flora are potential contributing factors to the development of GDM.In this paper,we review the literature on the changes in intestinal flora of women with GDM.

关 键 词：妊娠期糖尿病 肠道菌群 内毒素 胰岛素抵抗 短链脂肪酸 

分 类 号：R714[医药卫生—妇产科学]