缩宫素在剖宫产术中的合理应用分析  

Analysis of rational application of oxytocin in cesarean section

作　　者：罗月 王春蕾 Luo Yue;Wang Chunlei(Department of Pharmacy,Nanjing Hospital of Traditional Chinese Medicine,Nanjing 210000,China)

机构地区：[1]江苏省南京市中医院药剂科,江苏南京210000

出　　处：《实用妇科内分泌电子杂志》2021年第36期28-30,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的分析不同缩宫素使用方法在剖宫产术中的应用效果。方法选取于本院行剖宫产的产妇60例为研究对象,按不同缩宫素给药方式分为两组,每组30例。对照组采用宫体注射方式给药,研究组采用宫体注射+静脉滴注方式给药。比较两组的手术相关指标、生命体征指标及并发症发生情况。结果研究组手术用时为(41.11±3.74)min,短于对照组的(55.23±4.22)min,术中出血量、术中输液量、术后24 h出血量分别为(218.46±11.12)ml、(1131.53±22.52)ml、(67.11±3.62)ml,均少于对照组的(277.53±13.22)ml、(1256.28±25.22)ml、(78.42±3.66)ml,差异有统计学意义(P<0.05)。给药前,两组平均动脉压(MAP)、心率(HR)比较,差异无统计学意义(P>0.05);给药后10 min,研究组MAP高于对照组,HR低于对照组,差异有统计学意义(P<0.05)。研究组产后不良反应总发生率为13.33%,低于对照组的36.67%,差异有统计学意义(P<0.05)。结论在剖宫产中以宫体注射+静脉滴注方式使用卡贝缩宫素,可减少手术用时,提高安全性,促进术后康复,产妇术中生命体征更为平稳,术后不良反应更少。Objective To analyze the effect of different methods of using oxytocin in cesarean section.Methods 60 cases of puerpera who underwent cesarean section in our hospital were selected as research objects,and they were divided into two groups according to different ways of oxytocin administration,with 30 cases in each group.The control group was administered by intrauterine injection,while the study group was administered by intrauterine injection+intravenous drip.The operation-related indexes,vital signs and complications were compared between the two groups.Results The operation time of the study group was(41.11±3.74)min,which was shorter than(55.23±4.22)min of the control group,the intraoperative blood loss,intraoperative infusion volume and postoperative 24 h blood loss were(218.46±11.12)ml,(1131.53±22.52)ml and(67.11±3.62)ml,respectively,which were lower than(277.53±13.22)ml,(1256.28±25.22)ml and(78.42±3.66)ml in the control group,and the differences were statistically significant(P<0.05).Before administration,there were no significant differences in mean arterial pressure(MAP)and heart rate(HR)between the two groups(P>0.05);10 min after administration,the MAP of the study group was higher than that of the control group,IIR was lower than that of the control group,the differences were statistically significant(P<0.05).The total incidence of postpartum adverse reactions in the study group was 13.33%,lower than 36.67%in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of capetin by intrauterine injection and intravenous infusion during cesarean section can reduce the operation time,improve the safety,promote postoperative rehabilitation,more stable vital signs during obstetrics and gynecology,and less postoperative adverse reactions.

关 键 词：缩宫素 静脉滴注 宫体注射 剖宫产 应用效果 

分 类 号：R969.3[医药卫生—药理学] R719.8[医药卫生—药学]