妊娠期女性凝血功能检验的临床意义探析  

Clinical significance of coagulation function test in pregnant women

作　　者：吴玉芳 Wu Yufang(Department of Clinical Laboratory,Changzhou Wujin Hospital of Traditional Chinese Medicine,Changzhou 213161,China)

机构地区：[1]常州市武进中医医院检验科,江苏常州213161

出　　处：《实用妇科内分泌电子杂志》2021年第36期75-77,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探析妊娠期女性凝血功能检验的临床意义。方法选取于本院进行妊娠期定期检查的女性320例为研究组,另选取同时段于本院接受健康体检的女性152例为对照组,均进行凝血功能检验,比较两组的检测结果并分析产科并发症发生率。结果研究组中妊娠早期女性凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)与对照组比较,差异无统计学意义(P>0.05);研究组中妊娠中、晚期女性PT、APTT水平均低于对照组,TT、FIB水平均高于对照组,差异有统计学意义(P<0.05)。妊娠期低凝状态女性严重贫血、流产、产后大出血发生率分别为23.15%、19.44%、21.30%,均高于妊娠期高凝状态女性的1.42%、1.89%、2.83%,血栓栓塞发生率为1.85%,低于妊娠期高凝状态女性的11.32%,差异有统计学意义(P<0.05)。结论对妊娠期女性进行凝血功能检测,有利于出现异常情况的孕妇及早接受临床干预,对产科并发症的预防具有重要意义。Objective To explore the clinical significance of coagulation function test in pregnant women.Methods A total of 320 women who received regular check-up during pregnancy in our hospital were selected as the study group,and 152 women who received physical examination in our hospital at the same time were selected as the control group.Coagulation function lest was performed in both groups.The results of the two groups were compared and the incidence of obstetric complications was analyzed.Results There were no significant differences in prothrombin time(PT),activated partial thrombin time(APTT),thrombin time(TT)and fibrinogen(FIB)between the early pregnancy women in the study group and the control group(P>0.05);the levels of PT and APTT in second and third trimesters women of the study group were lower than those of the control group,and the levels of TT and FIB were higher than those of the control group,the differences were statistically significant(P<0.05).The incidence rates of severe anemia,abortion and postpartum massive hemorrhage of hypocoagulable women were 23.15%,19.44%and 21.30%,respectively,higher than 1.42%,1.89%and 2.83%of hypercoagulable women,and the incidence of thromboembolism was 1.85%,lower than 11.32%of hypercoagulable women,the differences were statistically significant(P<0.05).Conclusion The clinical significance of coagulation function test is helpful for pregnant women with abnormal conditions to receive clinical intervention as soon as possible,which is of great significance for the prevention of obstetric complications.

关 键 词：孕妇 妊娠期 凝血功能 产科并发症 检验价值 

分 类 号：R714.25[医药卫生—妇产科学]