基于模体相对电子密度刻度曲线修正锥形束CT图像的HU值  

Corrected HU Values of Cone-beam CT Images Based on Phantom Relative Electron Density Scale Curve

作　　者：洪加标 Hong Jiabiao(Clinical Oncology School of Fujian Medical University,Fujian Cancer Hospital,Fuzhou Fujian 350014,China)

机构地区：[1]福建医科大学肿瘤临床医学院·福建省肿瘤医院,福建福州350014

出　　处：《医疗装备》2022年第24期5-7,69,共4页Medical Equipment

基　　金：福建省肿瘤放射与免疫治疗临床医学研究中心(2020Y2012);福建省卫健委计划课题(2021CXB013);福建省科技计划项目(2021Y0052);福建医科大学启航基金项目资助(2020QH1223)。

摘　　要：目的基于CIRS-062标准模体刻度CT和锥形束CT(CBCT)图像的HU值与相对电子密度曲线,对CBCT图像的HU值进行修正,改善宫颈癌患者CBCT图像质量,为CBCT在自适应放射治疗(ART)中的应用创造条件。方法选取2021年1—12月福建省肿瘤医院行调强放射治疗(IMRT)的10例宫颈癌患者的治疗计划,通过开源软件3D Slicer中的Elastix模块对10例患者的CT和CBCT图像进行刚性配准,将CBCT图像的HU值映射为相应CT图像的HU值,得到高质量CBCT(HCBCT)图像,并通过均方误差(MAE)、峰值信号比(PSNR)和结构相似性(SSIM)3项指标量化评估图像质量。结果与CBCT-CT图像相比,HCBCT-CT图像HU值的MAE、PSNR和SSIM分别提升了50.7%、7.4%和4.6%。结论修正后的HCBCT图像各项指标相较于CBCT图像均有所提升,可以为CBCT图像在ART中的应用创造条件。Objective Based on the HU value and relative electron density curve of CIRS-062 standard phantom scale CT and cone beam CT(CBCT)images,the HU value of CBCT image was corrected,and the CBCT image quality of cervical cancer patients was improved,creating conditions for the application of CBCT in adaptive radiotherapy(ART).Methods With selection of treatment plans of 10 cervical cancer patients who received intensity modulated radiation therapy(IMRT)in Fujian Cancer Hospital from January to December 2021,CT and CBCT images of 10 patients were rigidly registered,through the Elastix module in the open source software 3D Slicer.The HU values of CBCT images were mapped to the HU values of the corresponding CT images to obtain a high-quality CBCT(HCBCT)images,and the image quality was quantitatively evaluated by three indicators:mean square error(MAE),peak to signal ratio(PSNR),and structural similarity(SSIM).Result Compared with CBCT-CT images,the MAE,PSNR and SSIM of HU values in HCBCT-CT images increased by 50.7%,7.4% and 4.6% respectively.Conclusion Compared with CBCT images,the corrected HCBCT images have improved in various indicators,which can create conditions for the application of CBCT images in ART.

关 键 词：CIRS-062标准模体 HU值修正 宫颈癌 HCBCT图像 量化评估 

分 类 号：R811[医药卫生—放射医学]