从肾虚血瘀论治多发性骨髓瘤周围神经病变  

Treatment of Multiple Myeloma Peripheral Neuropathy from Kidney Deficiency and Blood Stasis

作　　者：赵媛媛 刘朝霞[2] ZHAO Yuanyuan;LIU Zhaoxia(Shandong University of Traditional Chinese Medicine,Shandong Province,Ji'nan 250014,China;Hematology Department,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Shandong Province,Ji'nan 250014,China)

机构地区：[1]山东中医药大学,山东济南250014 [2]山东中医药大学附属医院血液科,山东济南250014

出　　处：《中国中医药现代远程教育》2023年第1期127-129,共3页Chinese Medicine Modern Distance Education of China

摘　　要：多发性骨髓瘤是第二常见的血液系统恶性肿瘤,具有不可治愈性。蛋白酶体抑制剂等药物的应用显著提高了患者的完全缓解率及总生存期,但随着药物的应用和疾病进展,高达60%的患者可出现不同程度的周围神经病变,从而影响了临床药物的选择及剂量调整,甚至导致停药,极大地降低了患者的临床疗效和生活质量。近年来,作者导师刘朝霞教授基于“肾虚血瘀”理论以“补肾益精、活血化瘀”为治疗原则,自拟益肾活血方治疗和缓解多发性骨髓瘤周围神经病变,在临床应用中取得一定的效果。Multiple myeloma is the second most common hematological malignancy, which is incurable. The application of proteasome inhibitors and other drugs has significantly improved the complete remission rate and overall survival of patients. However, with the application of drugs and disease progress, up to 60% of patients can have varying degrees of peripheral neuropathy, which affects the selection and dose adjustment of clinical drugs and even leads to drug withdrawal, which greatly reduces the clinical efficacy and quality of life of patients. In recent years, Professor Liu Zhaoxia based on the theory of“kidney deficiency and blood stasis”with“tonifying kidney and benefiting essence, promoting blood circulation and removing blood stasis”as the therapeutic principle, self-made tonifying the kidney and promoting blood circulation prescription in treating and relieving multiple myeloma peripheral neuropathy, and achieved a certain effect in clinical application.

关 键 词：骨痹 多发性骨髓瘤 周围神经病变 肾虚血瘀 益肾活血方 

分 类 号：R273[医药卫生—中西医结合]