夏枯草抗胃癌细胞的成分及其机制研究进展  

Research Progress on Xiakucao(Prunella vulgaris L.) against Gastric CancerC ells and Its Possible Mechanism

作　　者：张笑[1,2,3] 黄天生 李黎 ZHANG Xiao;HUANG Tiansheng;LI Li(Shanghai University of Traditional Chinese Medicine,Shanghai 200120,China;Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200050,China;Institute of Arthritis Research in Integrative Medicine,Shanghai Academy of Traditional Chinese Medicine,Shanghai 200050,China)

机构地区：[1]上海中医药大学,上海200120 [2]上海中医药大学附属光华医院,上海200050 [3]上海市中医药研究院中西医结合关节炎研究所,上海200050

出　　处：《中华中医药学刊》2022年第11期255-258,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：上海市卫生健康委员会科研项目(201940364);上海市长宁区卫生健康委员会科研项目(20214Z003)。

摘　　要：夏枯草(Prunella vulgaris L.)是一味在临床上常用的中药,具有清火泻火、明目、消肿散结的功效。其含有的丰富的化学成分,萜类、酚酸类、黄酮类、有机酸类等,通过各个通路,发挥着抗肿瘤、免疫调节、抗炎、抗氧化、抗菌、抗病毒等多种药理作用。近些年,夏枯草的抗肿瘤活性越来越受到重视,虽然对夏枯草性质的基础研究非常丰富,但用于临床的研究却很少。因此,就夏枯草中起到抗胃癌细胞作用的主要成分及其作用的通路、机制作以综述,以期对临床及科研人员有所帮助。Xiakucao(Prunella vulgaris L.)is a traditional Chinese medicine commonly used clinically,and has the effects of purging body fire,brightening eyes and reducing swelling.Its rich chemical components,such as terpenes,phenolic acids,flavonoids and organic acids,play effects of anti-tumor,immune regulation,anti-inflammatory,antioxidant,antibacterial,antiviral and other pharmacological.In recent years,more and more attention has been paid to the anti-tumor activity of Xiakucao(Prunella vulgaris L.).Although there are abundant basic studies on the properties of Xiakucao(Prunella vulgaris L.),clinical studies of it are scarce.Therefore,this article summarized the main components of Xiakucao(Prunella vulgaris L.)which had the function of resisting gastric cancer cells as well as their pathways and mechanisms,excepting to be helpful to clinical and scientific researchers.

关 键 词：夏枯草 胃癌细胞 中药 通路 化学成分 

分 类 号：R256.3[医药卫生—中医内科学]