负压封闭引流技术联合系统性湿性疗法治疗Ⅳ期压疮效果分析  

Effect analysis of negative pressure sealing drainage combined with systematic wet therapy on stage Ⅳ pressure ulcer

作　　者：张冰 ZHANG Bing(Affiliated Hospital of Guangdong Medical University,Zhanjiang 524023,China)

机构地区：[1]广东医科大学附属医院,广东湛江524023

出　　处：《临床医药实践》2023年第1期11-15,共5页Proceeding of Clinical Medicine

摘　　要：目的:评估负压封闭引流技术(VSD)联合系统性湿性疗法对Ⅳ期压疮患者的临床效果。方法:选择2020年1月—2022年2月的Ⅳ期压疮患者40例,按照随机方式分为观察组和对照组,每组20例。观察组采用VSD联合系统性湿性疗法,对照组采用系统性湿性疗法。评价两组压疮愈合计分表(PUSH)评分、视觉模拟(VAS)评分、创面面积、血红蛋白(Hb)、红细胞计数(RBC)、白细胞计数(WBC)、血清炎性因子、临床治疗参数、创面恢复情况及并发症发生率。结果:治疗前,两组PUSH评分、VAS评分和Hb, RBC,WBC及创面面积、血清炎性因子水平[白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]比较,差异无统计学意义(P>0.05)。治疗后,两组PUSH评分、VAS评分和WBC,IL-6及TNF-α低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组创面面积小于治疗前,且观察组小于对照组,差异有统计学意义(P<0.05);两组Hb和RBC高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组肉芽组织增生时间、住院时间短于对照组,换药次数、治疗费用少于对照组,创面恢复优良率高于对照组,并发症发生率低于对照组,差异均有统计学意义(P<0.05)。结论:对Ⅳ期压疮患者采用VSD联合系统性湿性疗法,能够减轻炎症反应,缩小创面面积,促进创面恢复,降低并发症风险。Objective: To evaluate the clinical effect of negative pressure sealing drainage(VSD) + systematic wet therapy on patients with stage Ⅳ pressure ulcer.Methods: Forty patients with stage Ⅳ pressure sore from January 2020 to February 2022 were randomly divided into observation group(n=20) and control group(n=20).The observation group was treated with VSD combined with systemic wet therapy, while the control group was treated with systemic wet therapy.The pressure ulcer healing score(PUSH),visual analogue scale(VAS),wound area, hemoglobin(Hb),red blood cell(RBC),white blood cell(WBC),serum inflammatory factors, clinical parameters, wound recovery and complications were evaluated.Results: Before treatment, there was no significant difference in push, VAS,wound area, Hb, RBC,WBC and serum inflammatory factor levels between the groups(P>0.05).After 21 days of treatment, the levels of push, VAS,wound area, Hb, RBC,WBC and serum inflammatory factors in the observation group were better(P<0.05).The granulation tissue proliferation time, hospital stay, dressing change times and treatment cost in the observation group were less than those in the control group, and the excellent and good rate of wound recovery(90.00%) was higher than that in the control group(60.00%),and the incidence of complications(5.00%) was lower than that in the control group(30.00%)(P<0.05).Conclusion: VSD + systemic wet therapy for patients with stage Ⅳ pressure ulcer can reduce inflammatory reaction, reduce wound area, promote wound recovery and reduce the risk of complications.

关 键 词：负压封闭引流技术 系统性湿性疗法 Ⅳ期压疮 

分 类 号：R632.1[医药卫生—外科学]