中国孤独症研究进展及前沿问题  

Research progress and frontier issues in ASDs in China

作　　者：武胜昔 郭保霖 WU Shengxi;GUO Baolin(Department of Neurobiology,School of Basic Medical Sciences,Air Force Medical University,Xi'an 710032,China)

机构地区：[1]空军军医大学基础医学院神经生物学教研室,陕西西安710032

出　　处：《空军军医大学学报》2022年第8期923-926,930,共5页Journal of Air Force Medical University

基　　金：科技部科技创新2030-“脑科学与类脑研究”重大项目(2021ZD0201005);国家自然科学基金重点项目(81730035);陕西省重点研发计划项目(2020ZDLSF01-09)。

摘　　要：孤独症(ASDs)是一组始于婴幼儿时期的神经发育障碍性疾病,典型症状包括社会交往障碍和重复刻板行为,往往伴随终身,给家庭和社会造成巨大的经济负担和精神压力,是严重的社会和科学问题。近年来我国学者在ASDs流行病学研究、遗传学研究及发病机制研究方向取得了系列原创性、突破性成果,从不同角度对ASDs的流行病学、病因学等方面进行了深入阐明。本文总结了我国近5年ASDs研究方面取得的系列发展成就,并对未来的研究方向作一展望,以期为我国ASDs后续研究提供参考。Autism spectrum disorders(ASDs)are a group of neurodevelopmental disorders that begin in infancy.The typical symptoms include social communication disorders and repetitive stereotypical behaviors,which often accompany for life,causing huge economic burdens and mental pressure on families and society.ASDs have become a serious social and scientific problem.In recent years,Chinese scholars have made a series of original and ground-breaking achievements in the epidemiology,genetics,and pathogenesis of ASDs.They have made in-depth elucidations on the epidemiology and etiology of ASDs from different perspectives.This paper summarized a series of achievements in ASDs research in China in recent five years,and prospected the future research directions,aiming to provide theoretical references for subsequent ASDs research in China.

关 键 词：孤独症 神经发育障碍 突触发育 神经环路 

分 类 号：R683[医药卫生—骨科学]