现代敷料促进创面愈合的研究进展  

Research progress of modern dressing in promoting wound healing

作　　者：彭毛东智 李毅[2] 王洪瑾[2] 杨文静 Peng Maodongzhi;Li Yi;Wang Hongjin;Yang Wenjing(Graduate School of Qinghai University,Xining 810016,China;Department of Burns and Plastic Surgey,Qinghai University Affiliated Hospital,Xining 810012,China)

机构地区：[1]青海大学研究生院,西宁810016 [2]青海大学附属医院烧伤整形外科,西宁810012

出　　处：《中华损伤与修复杂志（电子版）》2022年第4期354-358,共5页Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)

基　　金：青海省科学技术协会中青年托举工程项目(2019QHSKXRCTJ03);青海大学附属医院中青年科研基金项目(ASRF-2017-YB-06)。

摘　　要：随着科学技术的发展及生活水平的提高,人们对于创面治疗效率、创面愈合质量、治疗体验以及预后提出了更多、更高的要求,但医用纱布、棉垫等传统敷料因其功能局限性无法达到抗菌、止血、保湿等有利于创面愈合的效果。由此涉及高分子材料、有机化学、无机化学、生物化学等众多科学领域的现代敷料如雨后春笋般出现,是目前国内外发展非常迅速的一个领域。而如何赋予现代敷料有利于创面修复的功能以及使其接近完美是学者们长久以来的追求。故本文对现代敷料的发展、分类和其通过减弱创面炎症反应、加强创面抗菌能力、促进创面血管化、减少创面出血及改进自身理化特性促进创面愈合的机制进行相关总结。With the development of science and technology and the improvement of living standards,people have put forward more and higher requirements for wound treatment efficiency,wound healing quality,treatment experience and prognosis.However,traditional dressings such as medical gauze and cotton pad cannot achieve the effects of antibacterial,hemostatic and moisturizing for wound healing due to their functional limitations.As a result,modern dressings involving polymer materials,organic chemistry,inorganic chemistry,biochemistry and many other scientific fields have mushroomed and become a rapidly developing field at home and abroad.How to give modern dressings the function of beneficial to wound repair and make them close to perfection is the pursuit of scholars for a long time.Therefore,in this paper,the development and classification of modern dressings and their mechanisms of reducing wound inflammation,strengthening wound antibacterial ability,promoting wound vascularization,reducing wound bleeding and improving their physical and chemical properties to promote wound healing are summarized.

关 键 词：伤口愈合 生物敷料 炎症反应 抗菌 血管化 多功能化 

分 类 号：R64[医药卫生—外科学]