维持性血液透析患者营养不良与主动脉瓣钙化的关系  

The relationship between malnutrition and aortic valve calcification in patients with maintenance hemodialysis

作　　者：董怡晨 赵丹[1] 王佳 卿玲玲 王臻 董王钰 袁茜宁 杨晓萍[1] DONG Yi-chen;ZHAO Dan;WANG Jia(The First Affiliated Hospital of Shihezi University School of Medicine,Shihezi 832008,China)

机构地区：[1]石河子大学医学院附属第一医院,新疆石河子832008

出　　处：《吉林医学》2023年第1期51-55,共5页Jilin Medical Journal

摘　　要：目的:探讨维持性血液透析患者营养不良与主动脉瓣钙化的关系,并分析营养不良相关因素。方法:纳入2020年11月~2021年10月石河子大学第一附属医院行维持性血液透析患者128例,收集入组病例临床资料及实验室指标,通过营养不良炎性反应评分(MIS)评估营养不良程度,将患者分为轻度、中度、重度营养不良组。主动脉瓣钙化程度则采用心脏超声心动图评估。通过Spearman相关性分析验证营养不良的相关因素。结果:①MIS评分提示轻度、中度、重度营养不良分别为45例、43例和40例。②入选患者中主动脉瓣钙化48例,其发生率为37.5%,其中轻、中、重度主动脉瓣钙化分别为19例、17例和12例。③营养不良程度越重,主动脉瓣钙化发生率越高,程度越严重。④营养不良与年龄、主动脉瓣钙化积分和血清校正钙呈正相关,与体重指数(BMI)、前白蛋白、白蛋白呈负相关。控制年龄变量后,营养不良与主动脉瓣钙化仍为正相关。结论:营养不良与主动脉瓣钙化呈正相关,营养评估对维持性血液透析患者主动脉钙化的评价有重要的临床意义。Objective Discussion on the relationship between malnutrition and aortic valve calcification in patients with maintenance hemodialysis,and the related factors of malnutrition were analyzed.Method From November 2020 to October2021,128 patients with maintenance hemodialysis at the first Affiliated Hospital of Shihezi University were enrolled in the study.According to the malnutrition-inflammation score(MIS),the patients were divided into mild malnutrition group,moderate malnutrition group and severe malnutrition group.Echocardiography was used to detect the aortic valve calcification.The relative factors of malnutrition were analyzed by Spearman correlation.Results①MIS score showed that there were 45 cases of mild,moderate and severe malnutrition,43 cases and 40 cases respectively.②A total of 48 patients were found to have aortic valve calcification,the incidence rate was 37.5%,including 19 mild calcification,17 moderate calcification and 12 severe calcification.③The severe malnutrition group had the higher incidence and the more serious the aortic valve calcification.④Malnutrition was positively correlated with age,aortic valve calcification,and negatively correlated with BMI,prealbumin and albumin.Controlling for age variables,there was a positive correlation between malnutrition and aortic valve calcification.Conclusion Malnutrition is positively correlated with aortic valve calcification,and nutritional assessment is of great clinical significance for the assessment of aortic calcification in maintenance hemodialysis patients.

关 键 词：血液透析 营养不良 主动脉瓣钙化 

分 类 号：R692.5[医药卫生—泌尿科学] R542.52[医药卫生—外科学]