阿奇霉素联合阴道栓剂治疗非淋菌性宫颈炎的效果分析  

Analysis on Effect of Azithromycin Combined with Vaginal Suppositories in Treatment of Nongonococcal Cervicitis

作　　者：王秀艳 Wang Xiu-yan(Dongying District People's Hospital,Dongying 257000,Shandong Province,China)

机构地区：[1]东营市东营区人民医院,山东东营257000

出　　处：《中国社区医师》2022年第34期11-13,共3页Chinese Community Doctors

摘　　要：目的:分析非淋菌性宫颈炎患者采用阿奇霉素联合阴道栓剂治疗的临床效果。方法:选取2018年9月-2021年6月东营市东营区人民医院收治的非淋菌性宫颈炎患者60例为研究对象,根据随机数字表法分为对照组与观察组,各30例。对照组采用阿奇霉素治疗,观察组采用阿奇霉素联合阴道栓剂治疗。比较两组患者治疗效果、不良反应发生率、复发率、临床症状缓解时间及起效时间。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。治疗6、12个月,观察组复发率均低于对照组,差异有统计学意义(P<0.05);观察组宫颈水肿、分泌物异常、尿急尿痛临床症状缓解时间及起效时间短于对照组,差异有统计学意义(P<0.05)。结论:阿奇霉素联合阴道栓剂治疗非淋菌性宫颈炎患者临床效果显著,可改善患者临床症状,降低疾病复发率,缩短临床症状缓解时间及起效时间。Objective: To analyze the clinical effect of combined treatment of azithromycin and vaginal suppositories in patientswith nongonococcal cervicitis. Methods: Sixty patients with nongonococcal cervicitis admitted to Dongying District People’sHospital of Dongying City from September 2018 to June 2021 were selected as the study subjects. According to the random numbertable method, the patients were divided into control group and observation group, with 30 cases in each group. The control groupwas treated with azithromycin, and the observation group was treated with azithromycin combined with vaginal suppositories. Thetreatment effect, incidence of adverse reactions, recurrence rate, time to clinical symptom relief and time to onset of action werecompared between the two groups. Results: The total effective rate of treatment in the observation group was higher than that in thecontrol group, and the difference was statistically significant(P<0.05). There was no significant difference in the incidence ofadverse reactions between the two groups(P>0.05). After 6 and 12 months of treatment, the recurrence rate in the observationgroup was lower than that in the control group, and the difference was statistically significant(P<0.05). The time to clinicalsymptom relief of cervical edema, abnormal discharge, urgent micturition and dysuria and the time to onset of action in theobservation group were shorter than those in the control group, and the difference was statistically significant(P<0.05). Conclusion:Azithromycin combined with vaginal suppositories in the treatment of patients with nongonococcal cervicitis has significant clinicaleffect, it can improve the clinical symptoms of patients, reduce the recurrence rate of the disease, and shorten the time to clinicalsymptom relief and time to onset of action.

关 键 词：阿奇霉素 阴道栓剂 非淋菌性宫颈炎 

分 类 号：R711.32[医药卫生—妇产科学]