1型糖尿病成年患者的焦虑现状及其影响因素  

Anxiety current status of adult patients with type 1 diabetes mellitus and its influencing factors

作　　者：林晓仪[1] 李秀芹[1] 叶凯云[1] 梁干雄[1] LIN Xiao-yi;LI Xiu-qin;YE Kai-yun;LIANG Gan-xiong(Department of Endocrinology,Zhongshan City People′s Hospital,Zhongshan 528403,Guangdong,China)

机构地区：[1]广东省中山市人民医院内分泌科,广东省中山市528403

出　　处：《广西医学》2022年第22期2659-2663,共5页Guangxi Medical Journal

基　　金：广东省中山市卫生健康局医学科研项目(2019J020)。

摘　　要：目的了解1型糖尿病(T1DM)成年患者的焦虑现状,并分析其危险因素。方法纳入291例T1DM成年患者,收集其临床资料,采用焦虑自评量表(SAS)、抑郁自评表(SDS)分别评估其焦虑、抑郁症状。根据SAS结果将患者分为焦虑组(55例)和无焦虑组(236例),比较两组临床资料。采用二元Logistic回归分析影响T1DM成年患者发生焦虑的因素。结果焦虑组胰岛素用量、住院频率、合并糖尿病肾病比例、SDS评分、SAS评分、三酰甘油水平均高于无焦虑组,舒张压及β-羟基丁酸水平低于无焦虑组(均P<0.05)。二元Logistic回归分析结果显示,胰岛素用量、低血糖发生频率、SDS评分是成人T1DM合并焦虑的危险因素(均P<0.05)。结论T1DM成年患者焦虑发生率较高,胰岛素用量、低血糖发生频率、SDS评分是T1DM成年患者合并焦虑的危险因素。Objective To understand the anxiety current status of adult patients with type 1 diabetes mellitus(T1DM),and to analyze its risk factors.Methods A total of 291 adult patients with T1DM were enrolled,and their clinical data were collected.The patients′anxiety and depression symptoms were evaluated by the Self-Rating Anxiety Scale(SAS)and the Self-Rating Depression Scale(SDS),respectively.The patients were assigned to anxiety group(55 cases)or non-anxiety group(236 cases)according to the results of SAS.The clinical data were compared between the two groups.The factors affecting the occurrence of anxiety in adult patients with T1DM were analyzed by the binary Logistic regression.Results The anxiety group exhibited higher dosage of insulin,frequency of hospitalization,proportion of concomitant diabetic nephropathy,SDS score,SAS score,triacylglycerol level,whereas lower diastolic pressure,andβ-hydroxybutyrate level as compared with the non-anxiety group(all P<0.05).The results of binary Logistic regression analysis revealed that insulin dosage,frequency of the occurrence of hypoglycemia,SDS score were risk factors for adult patients with T1DM complicated with anxiety(all P<0.05).Conclusion The incidence rate of anxiety in adult patients with T1DM is high.Insulin dosage,frequency of the occurrence of hypoglycemia,SDS score are the risk factors for adult patients with T1DM complicated with anxiety.

关 键 词：1型糖尿病 成人 焦虑 抑郁 影响因素 

分 类 号：R587.1[医药卫生—内分泌]