Application and Influencing Factors of Radiofrequency Ablation in Monochorionic Pregnancy  

作　　者：Pingshan Pan Dongbing Huang Lu Tang Zuojan Yang Guican Qin Hongwei Wei 

机构地区：[1]Department of Obstetrics,Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi 530000,China [2]Department of Obstetrics and Gynecology Uitrasound,Matemal and Child Health Hospital of GuangxiZhuang Autonomous Region,Nanning,Guangxi 530000,China

出　　处：《Maternal-Fetal Medicine》2022年第4期245-250,共6页母胎医学杂志（英文）

基　　金：supported by Special fund for Guangxi science and technology base and talent(Gui Ke AD17129016);the Health Department of Guangxi Province Project(Z2016095)。

摘　　要：Objective: The aim of the study was to investigate the pregnancy outcomes and possible influencing factors concerning complicated monochorionic (MC) multiple pregnancies undergoing selective fetal reduction using radiofrequency ablation (RFA).Methods: This retrospective cohort study included 54 women with complicated MC multiple pregnancy who underwent selective fetal reduction using RFA at the Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region from January 2015 to March 2020. According to the indications for RFA, the 54 women were divided into three groups: complex complications (n = 30), structural anomalies (n = 18), and triplet pregnancy (n = 6). According to the gestational age for RFA, all patients were divided into three groups: 16-19+6 weeks (n = 17), 20-23+6 weeks (n = 17), and 24-26+6 weeks (n = 20). We analyzed the pregnancy outcomes (including the overall survival rate (OSR), gestational age at delivery, birth weight of newborns) and postoperative complications such as miscarriage, and intrauterine fetal death (IUFD) according to the indications and gestational age of reduction by using suitable statistical testing.Results: The OSR was 83.3% (45/54). The mean ± standard deviation (SD) of gestation at the time of reduction was 21.6 ± 3.2 weeks. The GA at delivery was 34.0(32.0,37.5) weeks. The mean ±SD of newborns’ birth weight was 2118 ± 685 g. The overall rates of miscarriage, PROM, and IUFD were 9.3% (5/54), 7.4% (4/54), and 7.4% (4/54), respectively. According to the indications for reduction, the OSR for complex complications, structural anomalies, and triplet pregnancy groups were 83.3% (25/30), 83.3% (15/18), and 83.3% (5/6), respectively. Statistically significant differences were only found in the mean birth weight among the three groups (P < 0.05). No significant difference was found in the rate of miscarriage, and mean gestation at delivery among the three groups (P > 0.05). In the group with complex complications, the OSR of twin-to-twin transfusion syndrome, selec

关 键 词：TWINS Monochorionic pregnancies Fetal reduction Radiofrequency ablation Pregnancy outcomes Influencing factors 

分 类 号：R714.23[医药卫生—妇产科学]