贵金属纳米材料在生物医学领域的应用进展  

Application Progress of Noble Metal Nanomaterials in Biomedical Field

作　　者：刘晓阳 陈佳琪 冯威 LIU Xiaoyang;CHEN Jiaqi;FENG Wei(School of Mechanical Engineering,Chengdu University,Chengdu 610106,China)

机构地区：[1]成都大学机械工程学院,四川成都610106

出　　处：《成都大学学报（自然科学版）》2022年第4期377-385,共9页Journal of Chengdu University（Natural Science Edition）

基　　金：成都大学引进人才科研启动项目(2081921109);成都大学研究生人才培养质量和教学改革项目(cdjgy2022034)。

摘　　要：与传统的医学手段相比,贵金属纳米颗粒具有良好的生物相容性、稳定性与强光散射等性质并且在可见光和近红外区域可进行等离子吸收,因此在生物医学领域迅速占据一席之地.在此基础上,对贵金属纳米(Ag NPs、Au NPs与Pt NPs)及其与其他物质(TiO_(2)、葡萄糖氧化酶、抗体与疫苗等)的组合在生物传感、生物成像、药物运输和肿瘤治疗等方面的性能进行探讨.最后,对贵金属纳米颗粒所提及的纳米医用领域的应用优势进行总结,并指出现存问题和对未来的期望.Compared with traditional medical methods,noble metal nanoparticles have good biocompatibility,stability,strong light absorption and other properties,and can perform plasma absorption in the visible and near-infrared regions.Therefore,it quickly occupies a place in the biomedical field.On this basis,the performances of noble metal nanoparticles(Ag NPs,Au NPs,Pt NPs)and their combinations with other substances(TiO_(2),glucose oxidase,antibodies,vaccines,etc.)in biosensor,bioimaging,drug transport and tumor treatment are discussed in this paper.Finally,the application advantages of noble metal nanoparticles in the field of nanomedicine are summarized and the existing problems and expectations for the future are pointed out.

关 键 词：贵金属纳米颗粒 生物传感 生物成像 药物运输 肿瘤治疗 生物医学 

分 类 号：TB383.1[一般工业技术—材料科学与工程] R318.08[医药卫生—生物医学工程]