MSCT显示脾脏密度一过性降低原因及与CRP的相关性  

MSCT showed the cause of transient decrease in spleen density and its correlation with CRP

作　　者：赵艳[1] 李娜[1] 王滔[1] 尹阳[1] 张笑[1] 郭济韬 ZHAO Yan;LI Na;WANG Tao;YIN Yang;ZHANG Xiao;GUO Jitao(Department of Radiology,The People's Hospital of Leshan,Leshan 614000,Sichuan,China)

机构地区：[1]乐山市人民医院放射医学科,四川乐山614000

出　　处：《西部医学》2023年第1期153-156,共4页Medical Journal of West China

摘　　要：目的探讨多层螺旋计算机断层扫描(MSCT)下脾脏密度一过性降低的原因及与C-反应蛋白(CRP)的相关性。方法纳入本院2016年9月~2021年4月的20例脾脏密度一过性降低患者,19例行MSCT平扫检查,1例行MSCT平扫+增强扫描,分析不同病种临床表现与相关实验室检查以及脾脏密度变化。结果20例患者中,急性胰腺炎(AP)12例,肿瘤术后6例,肺炎2例;20例脾脏密度弥漫性降低,平均(12.88±6.69)HU,治疗后脾脏密度恢复/回升,平均(42.61±3.97)HU;CRP治疗前均不同程度升高(211.03±106.70)mg/L,治疗后18例患者CRP显著降低(27.89±23.73)mg/L,2例未查。治疗前后脾脏密度变化及CRP值改变均有统计学差异(P<0.05),治疗前后脾脏密度值与CRP测值成负相关,其相关系数r分别为0.736、0.488(P<0.05)。结论脾脏密度一过性降低其病因多样,与炎性因子介导的炎性反应密切相关,对病情的严重程度和预后判定具有一定意义。Objective To investigate the causes of transient decrease of spleen density under MSCT and its correlation with C-reactive protein(CRP).Methods Twenty cases of transient decrease of spleen density in our hospital from September 2016 to April 2021 were analyzed retrospectively,including 19 cases of MSCT plain scan and 1 case of MSCT plain scan+enhanced scan.The clinical manifestations of different diseases and related laboratory examinations as well as the changes of spleen density were analyzed.Results Among the 20 cases,12 cases of acute pancreatitis(AP),6 cases of tumor after operation,and 2 cases of pneumonia.All the 20 cases of spleen density decreased diffusely,with an average CT value of(12.88±6.69)HU.After treatment,the spleen density recovered/increased with an average CT value of(42.61±3.97)HU.CRP increased in different degrees before treatment,with an average of(211.03±106.70)mg/L,and decreased significantly in 18 patients after treatment with an average of(27.89±23.73)mg/L,another 2 cases were not check CRP.There were significant differences in spleen density and CRP before and after treatment(P<0.05).There was a negative correlation between spleen density and CRP before and after treatment,and the correlation coefficients were 0.736 and 0.488,respectively(P<0.05).Conclusion The transient decrease of spleen density is caused by a variety of causes,which is closely related to the inflammatory response mediated by inflammatory factors.It is of great significance to determine the severity and prognosis of the disease.

关 键 词：脾脏 密度 C-反应蛋白 X线体层摄影术 

分 类 号：R445.3[医药卫生—影像医学与核医学]