粒细胞输注的临床应用进展  

Clinical application progress of granulocyte transfusion

作　　者：吴建君 崔欣[2] 赵树铭 WU Jianjun;CUI Xin;ZHAO Shuming(Guiqian Internaonal General Hospital;Guizhou Blood Center)

机构地区：[1]贵黔国际总医院输血科,贵阳贵州550018 [2]贵州省血液中心

出　　处：《中国输血杂志》2022年第11期1180-1183,共4页Chinese Journal of Blood Transfusion

摘　　要：粒细胞是血液中的含颗粒状白细胞,具有抗感染和抗肿瘤的重要作用。在临床输血中,对于患者严重感染而抗生素治疗无效、白细胞计数又极度低下时可采用异体粒细胞输注的方式进行抗感染治疗;近年来,采用粒细胞输注治疗癌症的研究取得了一些进展,有望采用具有高杀伤活性的异体粒细胞输注方式治疗某些特定类型癌症。Granulocyte is granular leukocytes in blood, which play an important role in anti-infection treatment and cancer-killing activity. In clinical, allogeneic granulocyte transfusion can be applied for anti-infection treatment when the patients are seriously infected but the antibiotic treatment is ineffective, especially the WBC counts are extremely low. Recently, some progress has been made in the researches about treating cancer with granulocyte infusion. It is possible to use allogeneic granulocyte infusion with high killing activity to treat the certain types of cancers.

关 键 词：粒细胞 输血 杀伤肿瘤活性 抗感染治疗 抗肿瘤治疗 

分 类 号：R457.1[医药卫生—治疗学] R557.3[医药卫生—临床医学]