多拉菌素注射剂对放牧牦牛草原革蜱的驱杀试验  

Effect of Doramectin Injection to Against Dermacentor nuttalli of Grazing Yak

作　　者：雷萌桐[1] 李春花[1] 蔡进忠[1] 铁成 LEI Meng-tong;LI Chun-hua;CAI Jing-zhong;TIE Cheng(Academy of Animal and Veterinary Science,Qinghai University,Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control,Xining 810016,China;Xinghai Animal Husbandry and Veterinary Station,Xinghai 813300,China)

机构地区：[1]青海省畜牧兽医科学院,青海省动物疾病病原诊断与绿色防控技术研究重点实验室,青海西宁810016 [2]兴海县畜牧兽医站,青海兴海813300

出　　处：《青海畜牧兽医杂志》2022年第5期10-13,共4页Chinese Qinghai Journal of Animal and Veterinary Sciences

基　　金：国家重点研发专项(2018YFD0502305);青海省重大科技专项(2016-NK-A7);青海大学中青年科研基金项目(2011-QNY-7)。

摘　　要：为评价新型抗寄生虫药物多拉菌素注射剂对寄生于放牧牦牛草原革蜱的驱杀效果,选用自然感染草原革蜱的放牧牦牛,采用给药后定期检查蜱死亡与存活情况的方法,进行驱杀效果观察。结果:多拉菌素注射剂各试验组给药后7 d、14 d、21 d检查,0.1 mg/kg体重剂量试验组对寄生于牦牛的革蜱转阴率在75.0%-91.7%,第14 d最高(91.7%),第21 d最低(75.0%),杀虫率在80.5%-87.2%,第7 d最低(80.5%),第21 d最高(87.2%);0.2 mg/kg组转阴率在91.7%-100.0%,第7 d、14 d最高(100.0%),第21 d最低(91,7%),杀虫率在94.4%-100%,第7 d、14 d最高(100%),第21 d最低(94.4%),0.3 mg/kg组转阴率和杀虫率均为100%;药物对照伊维菌素0.2 mg/kg组转阴率在83.3%-100%,第7 d、14 d最高(100%),第21 d最低(83.3%),杀虫率在91.6%-100%,第7 d、14 d最高(100%),第21 d最低(91.6%),低于同剂量多拉菌素注射剂的转阴效果及杀虫效果。试验结果证明,多拉菌素注射剂中、高剂量对放牧牦牛草原革蜱有高效驱杀作用。To evaluate the efficacy of doramectin injection against Dermacentor nuttalli, the grazing yaks of naturally infected with Ixodes were selected by regularly checking the death and survival of Ixodes after administration. The result showed that 7 th, 14 th, 21 th days after administration, The negative rate was 75.0%-91.7% of doramectin injection at the dose of 0.1 mg/kg body weight, and the lowest rate was on the 21 st day(75.0%),the highest was on the 14 th day(91.7%). The insecticidal rate was 80.5%-87.2%,the lowest was on the 7 st day(80.5%),the highest was on the 21 st day(87.2%). The negative rate was 91.7%-100.0%at the dose of 0.2 mg/kg, the lowest was on the 21 stday(91.7%),the highest was on the 7 th and 14 th days(100.0%);the Insecticidal rate was 94.4%-100.0%,the lowest on the 21 st day(94.4%), the highest was on the 7 th and 14 th(100.0%).The negative rate and Insecticidal rate were all 100.0%at the dose of 0.3 mg/kg;The negative rate of the control group with ivermectin 0.2 mg/kg was 83.3%-100%,the lowest was on the 21 st day(83.3%),the highest was on the 7 th and 14 th day(100%);the Insecticidal rate was 91.6%-100%,the lowest was on the 21 st day(91.6%),the highest was on the7 th and 14 th day(100%),and the efficacy was lower than the negative and Insecticidal at the same dose with doramectin injection. The results showed that the doramectin injection was efficiency against Dermacentor nuttalli of grazing yak at medium and high doses.

关 键 词：多拉菌素 放牧牦牛 草原革蜱 驱杀试验 

分 类 号：S855.9[农业科学—临床兽医学]