儿童左冠状动脉异常起源于肺动脉修复后的心肌应变指数表达分析  

Expression analysis of myocardial strain index after repair of abnormal origin of left coronary artery of pulmonary artery in children

作　　者：陈凌霄 王霄芳[1] 徐冠一 莫莹[1] Chen Lingxiao;Wang Xiaofang;Xu Guanyi;Mo Ying(Department of Pediatric Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)

机构地区：[1]首都医科大学附属北京安贞医院小儿心脏科,北京100029

出　　处：《中华胸心血管外科杂志》2022年第11期655-659,共5页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：目的研究儿童左冠状动脉异常起源于肺动脉(ALCAPA)修复后的心肌应变指数表达特征。方法对2017年8月至2021年8月ALCAPA修复患儿30例(研究组)的临床资料进行分析,另选取同期健康儿童作为对照组,观察比较研究组患儿治疗前、后及对照组纵向、周向、径向峰值心肌应变指数、收缩后应变指数(PSI)。结果研究组患儿治疗前及治疗后纵向、周向、径向整体峰值应变指数显著低于对照组,且研究组治疗后纵向、周向、径向整体峰值应变指数显著高于治疗前(P<0.05);研究组患儿治疗前纵向、周向、径向峰值应变指数显著低于对照组,研究组治疗后纵向下壁中间段、前壁中间段、前壁基底段、心尖部、周向下壁基底段、下壁中间段峰值应变指数显著低于对照组;且研究组治疗后纵向、周向、径向峰值应变指数显著高于治疗前(P<0.05);研究组患儿治疗前纵向、周向、径向PSI指数显著低于对照组,研究组治疗后纵向下壁中间段、间隔心尖段,周向下壁基底段、下壁中间段,径向PSI前壁基底段、心尖部显著高于对照组;且研究组治疗后纵向、周向、径向PSI显著低于治疗前(P<0.05)。结论ALCAPA修复后,整体和区域应变和整体同步性均有所改善,表明休眠心肌恢复,但异常左冠状动脉供应的某些节段的应变在ALCAPA修复后未能正常化,与一定程度的持续性心肌损伤一致,其可为ALCAPA患儿预后评估提供一定指导。Objective To study the expression characteristics of myocardial strain index after the abnormal origin of the left coronary artery of the pulmonary artery in children was repaired.Methods The data of 30 children(study group)with abnormal origin of pulmonary artery left coronary artery repair from August 2017 to August 2021 were analyzed.In addition,healthy children during the same period were selected as the control group,and the study group was compared before and after treatment and the control group.Circumferential and radial peak myocardial strain index,post-contraction strain index.Results The longitudinal,circumferential,and radial overall peak strain indexes of the study group before and after treatment were significantly lower than those of the control group,and the longitudinal,circumferential,and radial overall peak strain indexes of the study group after treatment were significantly higher than those before treatment(P<0.05);The longitudinal,circumferential,and radial peak strain indexes of the study group before treatment were significantly lower than those of the control group.After treatment in the study group,the middle section of the longitudinal inferior wall,the middle section of the anterior wall,the basal section of the anterior wall,the apex,and the circumferential direction were significantly lower The peak strain index of the basal segment of the inferior wall and the middle segment of the inferior wall was significantly lower than that of the control group;and the longitudinal,circumferential,and radial peak strain indexes of the study group after treatment were significantly higher than those before treatment(P<0.05);the study group children before treatment Longitudinal,circumferential,and radial PSI indexes were significantly lower than those of the control group.After treatment,the study group was treated in the longitudinal inferior wall,septal apical segment,circumferential inferior wall basal segment,inferior wall middle segment,and radial PSI anterior wall basal segment,apex.The pa

关 键 词：儿童 左冠状动脉异常起源于肺动脉 心肌应变指数 表达特征 

分 类 号：R725.4[医药卫生—儿科]