原位开窗技术和预开窗技术治疗胸主动脉疾病的系统评价及荟萃分析  

Systematic review and meta analysis of in situ fenestration and pre-fenestration in the treatment of thoracic aortic diseases

作　　者：林先东 王韧[1] 游斌 林胡昱 庄家祥 Lin Xiandong;Wang Ren;You Bin;Lin Huyu;Zhuang Jiaxiang(Department of Cardiovascular Surgery,Provincial Clinical College of Fujian Medical University,Fujian Provincial Hospital,Fuzhou 350001,China)

机构地区：[1]福建医科大学省立临床医学院福建省立医院心外科,福州350001

出　　处：《中华胸心血管外科杂志》2022年第11期688-698,共11页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：福建省自然科学基金重点项目(2020J02057);福建省立医院高水平医院建设科研基金(2017LHJJ01);福建省卫生健康科研人才培养项目(2019-CXB-5)。

摘　　要：胸主动脉疾病累及弓部分支血管,由于其复杂的解剖结构和变异多样,治疗具有挑战性。随着腔内修复技术的进步和发展,原位开窗技术和预开窗技术成为了治疗胸主动脉疾病的重要措施。近年来,少数中心已有应用原位开窗技术或预开窗技术的系列报道,初步结果令人满意。但存在术式单一、样本量小等问题,为了进一步比较分析两种术式之间的安全性和有效性,通过检索Pubmed、Embase、Cochrane、Web of Science、中国知网、万方数据、维普数据、中国生物医学文献数据库进行meta分析,发现两种术式在技术成功率、30天内死亡比例、内漏率、再干预率等方面未见明显统计学差异。对于术式的应用,可以根据患者病情和术者的临床经验进行抉择。Thoracic aortic disease,which involves some of the arch vessels,is challenging to treat because of its complex anatomical structure and variation.With the progress and development of endovascular repair technology,in situ fenestration and pre-fenestration have become important measures for the treatment of thoracic aortic diseases.In recent years,there have been a series of reports on the application of in situ fenestration or pre-fenestration in a few centers,and the preliminary results are satisfactory.However,there are some problems such as single operation and small sample size.In order to further compare and analyze the safety and efficacy between the two operations,meta-analysis was conducted by searching Pubmed,Embase,Cochrane,Web of Science,China National Knowledge Infrastructure,Wanfang data,VIP data and China Biology Medicine disc.There was no significant difference in technical success rate,30-day mortality,endoleak rate and reintervention rate between the two methods.The application of surgical methods can be determined according to the patient's condition and the surgeon's clinical experience.

关 键 词：META分析 死亡比例 中国知网 荟萃分析 检索 样本量 

分 类 号：R654.3[医药卫生—外科学]