脓毒症并发ARDS的发病机制及预后评估研究进展  

Research Progress on Pathogenesis and Prognosis Evaluation of Sepsis Complicated with ARDS

作　　者：张曌 黄斌[1] ZHANG Zhao;HUANG Bin(Intensive Care Unit,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属第二医院重症医学科,重庆400010

出　　处：《医学信息》2022年第23期176-180,共5页Journal of Medical Information

基　　金：重庆市卫生局医学科研计划项目(编号:2009-2-165)。

摘　　要：脓毒症并发急性呼吸窘迫综合征(ARDS)发病机制复杂,其确切机制尚未完全阐明,涉及血管内皮损伤、免疫失调、信号传导、基因易感等方面。脓毒症并发ARDS的预后与患者是否合并基础疾病、感染部位、生物标志物、部分临床指标等相关。本文对脓毒症与ARDS进行概述,并对脓毒症并发ARDS的发病机制和预后相关危险因素进行综述,以期为临床治疗提供参考。The complex pathogenesis of sepsis complicated with acute respiratory distress syndrome(ARDS)has not been fully elucidated,involving vascular endothelial injury,immune disorders,signal transduction,genetic susceptibility and so on.The prognosis of sepsis complicated with ARDS is related to whether the patient has underlying diseases,infection sites,biomarkers,and some clinical indicators.This article summarizes sepsis and ARDS,and reviews the pathogenesis and prognostic risk factors of sepsis complicated with ARDS,in order to provide reference for clinical treatment.

关 键 词：脓毒症 急性呼吸窘迫综合征 免疫失调 

分 类 号：R631.2[医药卫生—外科学]