儿童多系统炎症综合征诊治进展  

Advances in diagnosis and treatment of multisystem inflammatory syndrome in children

作　　者：唐家琢(综述) 刘苗[1] 梁章武[1] 姜毅(审校)[1] Tang Jiazhuo;Liu Miao;Liang Zhangwu;Jiang Yi(Department of Pediatrics,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院儿科,430060

出　　处：《国际儿科学杂志》2022年第11期728-733,共6页International Journal of Pediatrics

基　　金：中央高校基本科研业务费专项资金资助项目(2042020kf1011)。

摘　　要：严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2, SARS-CoV-2)感染可能会导致儿童多系统炎症综合征(multisystem inflammatory syndrome in children, MIS-C)。MIS-C多发于较大年龄儿童及青少年, 患儿有SARS-CoV-2感染的实验室或流行病学证据, 临床表现包括持续发热、低血压、炎症标志物升高及多器官受累症状, 与川崎病有一定相似性。一旦起病, 可在短时间内进展并恶化, 大多数患儿需要接受重症监护治疗, 尽管整体预后良好, 但是仍有部分患儿出现死亡等不良结果, 应加强对疑似患儿的监护和管理, 提高对该病的诊治水平。Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection may lead to multisystem inflammatory syndrome in children(MIS-C).MIS-C mostly occurs in older children and adolescents who have laboratory or epidemiological evidence of SARS-CoV-2 infection.The clinical manifestations include persistent fever,hypotension,elevated inflammation markers,and symptoms of multiple organ involvement,which is similar to Kawasaki disease.Once the disease occurs,it can progress rapidly and worsen in a short time,and most children require intensive care admission.Although the overall prognosis is good,some patients have adverse results such as death.We should strengthen the monitoring and management of suspected children and improve the level of diagnosis and treatment of the disease.

关 键 词：儿童 儿童多系统炎症综合征 严重急性呼吸综合征冠状病毒2 新型冠状病毒肺炎 川崎病 

分 类 号：R725[医药卫生—儿科]