物理康复联合小青龙汤治疗儿童哮喘缓解期肺脾气虚证的效果  

Effect of physical rehabilitation combined with Xiaoqinglong Decoction on the syndrome of lung and spleen deficiency in children with asthma remission

作　　者：孙安兵 杨殿福[2] 户晓艳 SUN Anbing;YANG Dianfu;HU Xiaoyan(Department of Traditional Chinese Medicine,Dunhuang Traditional Chinese Medicine Hospital,Jiuquan 736200;Tangshan Vocational&Technical School,Tangshan 063099,China)

机构地区：[1]敦煌市中医医院中医内科,甘肃酒泉736200 [2]唐山职业技术学院,河北唐山063099

出　　处：《西安交通大学学报（医学版）》2023年第1期142-146,共5页Journal of Xi’an Jiaotong University（Medical Sciences）

摘　　要：目的探讨物理治疗联合中医培土生金法治疗儿童哮喘缓解期肺脾气虚证的效果及对血清学指标的影响。方法择2018年5月—2020年5月于我院就诊的哮喘缓解期患儿130例,随机分为联合组(n=65)与物理组(n=65),物理组采用物理治疗、孟鲁司特钠咀嚼片治疗,联合组给予物理治疗和基于培土生金法的小青龙汤,两组均治疗3个月。比较两组治疗疗效,治疗前及治疗后胸闷(发作)、咳嗽、气喘、喉间喘鸣主要中医症状积分。记录治疗前(T0)、治疗1、2、3个月后(T1、T2、T3),治疗后第6、9个月随访(T4、T5)中医综合征平均评分。并于治疗前及治疗后采集患儿血清并检测肿瘤坏死因子α(tumor necrosis factorα,TNF-α)、免疫球蛋白E(immunoglobulin,Ig E)、白细胞介素6(interleukin 6,IL-6)水平。结果治疗后联合组患儿治疗总有效率(86.15%)高于物理组(73.85%)(χ^(2)=4.333,P<0.05)。治疗后气喘、喉间痰鸣的中医证候积分均降低且联合组低于物理组(P<0.05)。T3、T4及T5联合组中医证候平均积分低于物理组(t=3.167、3.317、4.168、4.267,P<0.05)。治疗后两组IL-6、IgE及TNF-α水平均降低(P<0.05),联合组IgE及TNF-α水平均低于物理组(t=12.164、5.136,P<0.05)。结论物理治疗联合基于小青龙汤对儿童哮喘缓解期肺脾气虚证疗效确切,可以改善临床症状,调节免疫。Objective To investigate the effect of physical therapy combined with traditional Chinese medicine(TCM)in treating the syndrome of lung and spleen qi deficiency in children at asthma remission stage and the effect on serological indicators.Methods A total of 130 children with asthma in remission treated in our hospital from May 2018 to May 2020 were selected and randomly divided into combination group(n=65)and physical group(n=65).The physical group was treated with physical therapy and Montelukaste sodium chewable tablet,while the combination group was treated with Xiaoqinglong Decoction based on soil preparation and gold generation method.Both groups were treated for three months.The scores of chest tightness(attack),cough,asthma and laryngeal wheezing were compared between the two groups before and after treatment.The average score of TCM syndrome was recorded before treatment(T0),1,2 and 3 months after treatment(T1,T2 and T3),and 6 and 9 months after treatment(T4 and T5).Serum levels of interleukin 6(IL-6),immunoglobulin(IgE)and tumor necrosis factorα(TNF-α)were detected before and after treatment.Results After treatment,the total effective rate in the combination group(86.15%)was higher than that in the physical group(73.85%)(χ^(2)=4.333,P<0.05).After treatment,the TCM syndrome scores of asthma,laryngeal phlegm were significantly lower in the combination group than in the physical group(P<0.05).The average score of TCM syndrome in T3,T4 and T5 combination group was lower than that in the physical group(t=3.167,3.317,4.168,4.267,P<0.05).After treatment,the levels of IL-6,IgE and TNF-αwere decreased(P<0.05),and the levels of IgE and TNF-αin the combination group were lower than those in the physical group(t=12.164,5.136,P<0.05).Conclusion Physical therapy combined with Xiaoqinglong Decoction can improve clinical symptoms and regulate immunity of children at asthma remission stage.

关 键 词：物理治疗 小青龙汤 儿童哮喘缓解期 肺脾气虚证 

分 类 号：R452[医药卫生—治疗学]