早期心肺康复训练联合生物反馈疗法在冠状动脉搭桥术后患者中的康复效果及对心肺功能、认知功能的影响  

Rehabilitation Effect of Early Cardiopulmonary Rehabilitation Training Combined with Biofeedback Therapy on Patients after Coronary Artery Bypass Grafting and its Effect on Cardiopulmonary Function and Cognitive Function

作　　者：程珺瑶 管玉珍[1] 李莹莹[1] 耿丹丹 孙运良 CHENG Jun-yao;GUAN Yu-zhen;LI Ying-ying;GENG Dan-dan;SUN Yun-liang(Department of Cardiovascular Surgery,Jiangsu Provincial People's Hospital,Nanjing,Jiangsu,210029,China)

机构地区：[1]江苏省人民医院心脏大血管外科,江苏南京210029

出　　处：《现代生物医学进展》2022年第21期4055-4059,共5页Progress in Modern Biomedicine

基　　金：江苏省自然科学基金项目(BK201506417)。

摘　　要：目的:观察早期心肺康复训练联合生物反馈疗法在冠状动脉搭桥术(CABG)后患者中的康复效果及对心肺功能、认知功能的影响。方法:选择2019年4月~2021年11月期间江苏省人民医院接收的择期行CABG的患者100例,根据信封抽签法将患者分为对照组和观察组,各为50例,对照组给予早期心肺康复训练,观察组给予早期心肺康复训练联合生物反馈疗法,观察两组康复效果、心肺功能指标变化、神经元特异性烯醇化酶(NSE)、S-100β蛋白、认知功能损伤情况。结果:观察组的首次排气时间、首次下床时间、住院时间短于对照组(P<0.05)。干预后,两组左心室射血分数(LVEF)、心脏指数(CI)、左心室短轴缩短分数(LVFS)、6 min内行走的最大距离(6WMT)升高,且观察组高于对照组(P<0.05)。干预后,两组用力肺活量(FVC)、1秒用力呼气容积(FEV1)、FEV1/FVC升高,且观察组高于对照组(P<0.05)。干预后,两组蒙特利尔认知功能评估量表(MoCA)评分升高,且观察组高于对照组(P<0.05)。干预后,两组神经元特异性烯醇化酶(NSE)、S-100β蛋白降低,且观察组低于对照组(P<0.05)。结论:早期心肺康复训练联合生物反馈疗法干预CABG术后患者,可促进心肺功能改善,减轻认知功能损伤,调节血清NSE、S-100β蛋白水平,提高康复效果。Objective: To observe the rehabilitation effect of early cardiopulmonary rehabilitation training combined with biofeedback therapy in patients after coronary artery bypass grafting(CABG) and its effect on cardiopulmonary function and cognitive function.Methods: 100 patients who received CABG in Jiangsu Provincial People’s Hospital from April 2019 to November 2021 were selected.According to the envelope lottery method, the patients were divided into control group and observation group, with 50 cases in each group. The control group was given early cardiopulmonary rehabilitation training, and the observation group was given early cardiopulmonary rehabilitation training combined with biofeedback therapy. The rehabilitation effects, changes of cardiopulmonary function indexes, neuron specific enolase(NSE), S-100β protein and cognitive impairment in two groups were observed. Results: The first exhaust time, the first time out of bed and the hospital stay in the observation group were shorter than those in the control group(P<0.05). After intervention, the left ventricular ejection fraction(LVEF), cardiac index(CI), left ventricular short axis shortening fraction(LVFS) and the maximum walking distance within 6 minutes(6WMT) were increased in two groups, and the observation group was higher than the control group(P<0.05). After intervention, the forced vital capacity(FVC), forced expiratory volume in one second(FEV1) and FEV1/FVC in the two groups increased, and the observation group was higher than the control group(P<0.05). After intervention, the score of Montreal cognitive function assessment scale(MoCA) increased in the two groups, and the observation group was higher than the control group(P<0.05). After intervention, neuron specific enolase(NSE) and S-100β protein were decreased in two groups, and the observation group was lower than the control group(P<0.05). Conclusion: Early cardiopulmonary rehabilitation training combined with biofeedback therapy can improve cardiopulmonary function, reduce cognitive impa

关 键 词：早期心肺康复训练 生物反馈疗法 冠状动脉搭桥术 康复效果 心肺功能 认知功能 

分 类 号：R541.4[医药卫生—心血管疾病] R493[医药卫生—内科学]