乳香与没药相须配伍特征分析及其现代研究进展与展望  

Combination characteristics of frankincense and myrrh and progress and prospect of their combination efficacy and mechanism

作　　者：宿树兰[1] 缪晓冬 李佳晌 赵丽辉 范若颖 尚尔鑫[1] 朱悦[1] 钱大玮[1] 段金廒[1] SU Shu-lan;MIAO Xiao-dong;LI Jia-shang;ZHAO Li-hui;FAN Ruo-ying;SHANG Er-xin;ZHU Yue;QIAN Da-wei;DUAN Jin-ao(Jiangsu Blood-regulating Prescription Innovative Drug Engineering Center,Jiangsu Key Laboratory for Traditional Chinese Medicine Formulae Research,Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae,National-Local Joint Engineering Research Center of Resourcs Industrialization of Chinese Meteria Medica and Prescription-oriented Innovative Drugs,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization,Nanjing University of Chinese Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学,江苏省中药资源产业化过程协同创新中心,中药资源产业化与方剂创新药物国家地方联合工程研究中心,江苏省方剂高技术研究重点实验室,江苏省方剂研究重点实验室,江苏省理血方剂创新药物工程中心,江苏南京210023

出　　处：《中国中药杂志》2022年第21期5789-5796,共8页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金面上项目(30973885,82274086);江苏省高等学校基础科学(自然科学)重大项目(21KJA360010);江苏省中药资源产业化过程协同创新中心重点项目(ZDXM-2020-24);江苏省高校优秀科技创新团队项目(2021)。

摘　　要：药对的认识和形成是医家在长期的临床实践中对其药性深刻理解与感悟的经验总结,逐步成为中医遣药组方的精妙结构单元,常常在方剂配伍中起到核心和桥梁作用。乳香与没药均来自于域外的树脂类熏香原料,后归化为中药并赋予其丰富的药性内涵,成为宣通脏腑、活血止痛之常用药味,具有确切的临床疗效。该文基于临床应用角度,系统梳理和挖掘分析了乳香与没药相须配伍及配比结构、功效表征及其治疗病证,以及配伍功效物质与作用机制等科学内涵。在此基础上,对乳香-没药进一步深入研究重点和应用前景进行展望,以期为进一步揭示该药对相须配伍成方用药的潜在规律,服务于中医临床及中药新药创新,为中药药性认识及药对配伍研究提供参考与借鉴。Herbal pair is formed based on the experience summary of doctors′ deep understanding and perception of the medicinal nature in long-term clinical practice. It gradually becomes the exquisite structural unit for preparing traditional Chinese medicine(TCM) prescriptions, and often plays a core bridge role in the prescription combination. Frankincense and myrrh are raw resin materials of incense abroad, which are subsequently included as Chinese medicinal herbs and endowed with rich medicinal connotation. With the functions of relaxing Zang-fu organs, activating blood and relieving pain, they have definite clinical efficacy. From the perspective of herbal description and clinical application, this study systematically analyzed the combination of frankincense and myrrh as well as their combination proportion, efficacy characterization, diseases and syndromes, effective components and action mechanism. On this basis, the focus of in-depth research of frankincense-myrrh and the application prospects were proposed, in order to further reveal the potential meditation law of this herbal pair, thus contributing to clinical practice and drug innovation of traditional Chinese medicine, and providing reference for understanding of TCM medicinal nature and research of herbal pairs.

关 键 词：乳香 没药 药对 药性 相须配伍 功效物质 作用机制 

分 类 号：R289.1[医药卫生—方剂学]