以孤立性天门冬氨酸转氨酶升高为表现的儿童巨天门冬氨酸转氨酶血症1例  

A case report of macro-AST with isolated elevated aspartate aminotransferase in a child

作　　者：张晋[1] 吴丽娜[1] 刘文翰 秦晓松[1] Zhang Jin;Wu Li′na;Liu Wenhan;Qin Xiaosong(Department of Laboratory Medicine,Shengjing Hospital of China Medical University,Liaoning Clinical Research Center for Laboratory Medicine,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院检验科,辽宁省医学检验临床医学研究中心,沈阳110004

出　　处：《中华检验医学杂志》2022年第12期1279-1281,共3页Chinese Journal of Laboratory Medicine

摘　　要：当临床中遇到无法解释的天门冬氨酸转氨酶(AST)活性升高时,需要考虑到巨天门冬氨酸转氨酶血症的可能。本病例为1例3岁女童发现血清AST活性孤立性升高,围绕引起AST升高的常见病因进行检查,未发现明显异常。应用聚乙二醇沉淀法检测,其沉淀活性为98.7%,诊断为巨天门冬氨酸转氨酶血症。We need to consider the macro-AST when the elevated AST activity cannot be explained.A 3-year-old child was found to have an increase in serum AST activity,but no obvious abnormality be found ofter examination.The PEG precipitation assay showed that the activity was 98.7%,which was diagnosed as macro-AST.

关 键 词：天门冬氨酸转氨酶 巨天门冬氨酸转氨酶 聚乙二醇 聚乙二醇沉淀法 

分 类 号：R725[医药卫生—儿科]