离散选择实验应用于高血压诊疗偏好的研究进展  

Research Progress of Discrete Choice Experiment Applied to Diagnosis and Treatment Preference of Hypertension

作　　者：刘瑞 徐娟 刘博 郑二维[2] 李金梅 常恩雪 郑万基 李浩飞 黄卫东[1] 罗南[4] LIU Rui;XU Juan;LIU Bo;ZHENG Er-Wei;LI Jin-Mei;CHANG En-Xue;ZHENG Wan-Ji;LI Hao-Fei;HUANG Wei-Dong;LUO Nan(School of Health Management,Harbin Medical University,Harbin 150081,China;Operations Management Division of First Affiliated Hospital of Harbin Medical University,Harbin 150001,China;Heilongjiang Provincial Health Publicity Education and Information Center,Harbin 150028,China;Saw Swee Hock School of Public Health,National University of Singapore,Singapore 117549)

机构地区：[1]哈尔滨医科大学卫生管理学院,哈尔滨150081 [2]哈尔滨医科大学附属第一医院运营管理部,哈尔滨150001 [3]黑龙江省卫生健康管理服务评价中心,哈尔滨150028 [4]新加坡国立大学苏瑞福公共卫生学院,新加坡117549

出　　处：《中国药物经济学》2022年第11期10-15,共6页China Journal of Pharmaceutical Economics

基　　金：美国中华医学基金会(CMB-19-308);国家自然科学基金(71974048)。

摘　　要：目的系统梳理离散选择实验(DCE)在高血压诊疗偏好研究中的进展,为开展相关研究提供参考与借鉴以及为高血压防治提供循证依据。方法系统检索DCE与高血压诊疗偏好相关的中英文文献,从DCE属性及水平的确定、实验设计、数据收集和数据分析以及主要研究发现方面对纳入文献进行系统梳理和总结。结果共检索文献128篇,最终纳入文献5篇。分析结果显示:1)纳入的研究多采用文献回顾方法设定属性及水平,缺少定性访谈对理论属性及水平的补充;2)纳入的研究多采用正交设计来创建选择集,缺少高效实验设计的应用;3)心血管风险降低、药物不良反应以及医生与患者互动的质量是高血压患者在诊疗中优先考虑的因素;4)缺少供需视角下高血压诊疗偏好的研究。结论在开展基于DCE高血压诊疗偏好的研究时,应综合使用文献回顾和定性访谈方法开发属性及水平,同时应增加高效实验设计方法的应用,优先考虑心血管风险降低、药物不良反应以及医生与患者互动质量的相关属性,并从供需视角了解高血压诊疗偏好,以促进医患共同决策,为精准提供高血压诊疗服务贡献决策依据。Objective The purpose of this study was to review systematically discrete choice experiment of diagnosis and treatment of hypertension,it could provide reference for related research and evidence-based basis for hypertension prevention and treatment.Methods A systematic review of DCEs of diagnosis and treatment of hypertension was undertaken from Chinese and English literatures.The application status of DCEs was analyzed and summarized from the aspect of attributes and levels,experimental design,data collection,econometrics analysis and the preference results.Results A total of 128 literatures were retrieved,involving 5 valid literatures.The included studies mostly used literature review to set the attributes and levels,and lacked the supplement of qualitative interviews to the theoretical attributes and levels.Orthogonal experiment designs were used more frequently to create the DCE choice sets and lacked the application of D-efficient experiment designs.Cardiovascular risk reduction,adverse drug reactions,and the quality of physician-patient interaction are priorities for patients with hypertension.There is a lack of research on diagnosis and treatment preference of hypertension treatment preferences from the perspective of supply and demand.Conclusion When carrying out studies based on DCE hypertension diagnosis and treatment preferences,we should comprehensively use the methods of literature review and qualitative interviews to develop attributes and levels,and increase the application of D-efficient experimental design methods,give priority to cardiovascular risk reduction of adverse drug reactions and the quality of interaction between doctors and patients,and understand hypertension diagnosis and treatment preferences from the perspective of supply and demand,so as to promote doctors-patients’joint decision-making.To provide decision-making basis for the accurate provision of hypertension diagnosis and treatment services.

关 键 词：高血压 离散选择实验 偏好 

分 类 号：R544.1[医药卫生—心血管疾病]