中国儿童A族链球菌感染相关疾病的诊断、治疗与预防专家共识  

Chinese experts′consensus statement on diagnosis,treatment and prevention of Group A Streptococcus infection related diseases in children

作　　者：禹定乐[1,2] 卢清华 尤元海 张海邻[4] 陆敏[5,6] 徐保平[7] 刘钢 马琳[9] 梁云梅[10] 刘盈[9] 马耀玲[11] 何颜霞[12] 姚开虎 俞桑洁[2] 乔红梅 刘琮 刘小荣[15] 樊剑锋[15] 高立伟[7] 叶继锋[16] 王传清[17] 马香[18] 邓江红 卢根[20] 成焕吉[13] 张文双 徐佩茹[22] 殷俊[23] 符州 常贺生[10] 张国成[25] 郑跃杰[1] 申昆玲 杨永弘[1,2] Yu Dingle;Lu Qinghua;You Yuanhai;Zhang Hailin;Lu Min;Xu Baoping;Liu Gang;Ma Lin;Liang Yunmei;Liu Ying;Ma Yaoling;He Yanxia;Yao Kaihu;Yu Sangjie;Qiao Hongmei;Liu Cong;Liu Xiaorong;Fan Jianfeng;Gao Liwei;Ye Jifeng;Wang Chuanqing;Ma Xiang;Deng Jianghong;Lu Gen;Cheng Huanji;Zhang Wenshuang;Xu Peiru;Yin Jun;Fu Zhou;Chang Hesheng;Zhang Guocheng;Zheng Yuejie;Shen Kunling;Yang Yonghong(Department of Respiration,Shenzhen Children′s Hospital,Shenzhen 518038,China;Microbiology Laboratory,Beijing Pediatric Research Institute,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Diagnosis for Communicable Diseases,State Key Laboratory for Infectious Disease Prevention and Control,National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Department of Respiration,Yuying Children′s Hospital of Wenzhou Medical University,Wenzhou 325027,China;Department of Respiration,Children′s Hospital Affiliated to Shanghai Jiaotong School of Medicine,Shanghai 200062,China;Department of Pediatrics,Shanghai United Family Hospital,Shanghai 200336,China;Department of Respiratory Disease I,Beijing Children′s Hospital,Capital Medical University,China National Clinical Research Center of Respiratory Diseases,National Center for Children′s Health,Beijing 100045,China;Department of Infectious Diseases,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Dermatology,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Pediatrics,Beijing Chaoyang Hospital Affiliated to Capital Medical University,Beijing 100020,China;Department of Emergency,Wuhan Children′s Hospital,Tongji Medical College,Huazhong University of Science&Technology,Wuhan 430019,China;Pediatric Intensive Care Unit,Shenzhen Children′s Hospital,Shenzhen 518038,China;Pe

机构地区：[1]深圳市儿童医院呼吸科,深圳518038 [2]国家儿童医学中心,首都医科大学附属北京儿童医院,北京市儿科研究所微生物研究室,北京100045 [3]传染病预防控制国家重点实验室,中国疾病预防控制中心传染病预防控制所传染病诊断室,北京102206 [4]温州医科大学附属育英儿童医院儿童呼吸科,温州325027 [5]上海交通大学附属儿童医院呼吸科,上海200062 [6]上海和睦家医院儿科,上海200336 [7]国家儿童医学中心,国家呼吸系统疾病临床医学研究中心,首都医科大学附属北京儿童医院呼吸一科,北京100045 [8]国家儿童医学中心,首都医科大学附属北京儿童医院感染内科,北京100045 [9]国家儿童医学中心,首都医科大学附属北京儿童医院皮肤科,北京100045 [10]首都医科大学附属北京朝阳医院儿科,北京100020 [11]华中科技大学同济医学院附属武汉儿童医院急诊科,武汉430019 [12]深圳市儿童医院重症医学科,深圳518038 [13]吉林大学第一医院小儿呼吸科,长春130021 [14]深圳市儿童医院心血管内科,深圳518038 [15]国家儿童医学中心,首都医科大学附属北京儿童医院肾内科,北京100045 [16]温州医科大学附属育英儿童医院药学部,温州325027 [17]国家儿童医学中心,复旦大学附属儿科医院临床检验中心细菌实验室,上海201102 [18]山东大学附属儿童医院(济南市儿童医院)呼吸科,济南250022 [19]国家儿童医学中心,首都医科大学附属北京儿童医院风湿科,北京100045 [20]广州市妇女儿童医疗中心呼吸科,广州510620 [21]天津市儿童医院感染科,天津300074 [22]新疆医科大学儿科学院,乌鲁木齐830011 [23]安徽医科大学第一附属医院感染病科,合肥230022 [24]国家儿童健康与疾病临床研究中心,重庆医科大学附属儿童医院呼吸科,重庆400014 [25]陕西中医药大学第二附属医院儿童医院重症医学科,咸阳712046

出　　处：《中华实用儿科临床杂志》2022年第21期1604-1618,共15页Chinese Journal of Applied Clinical Pediatrics

基　　金：国家卫生健康委抗菌药物临床应用与耐药评价专家委员会项目(KJYWZWH-OT-02-2021-06);广东省高水平临床重点专科(深圳市配套建设经费)(SZGSP012);深圳市医学重点学科建设经费(SZXK032)。

摘　　要：A族链球菌(Group A Streptococcus,GAS)是最常见的病原体之一,尤其对于儿童。在全球范围内,GAS感染是导致发病和死亡的重要原因。但GAS造成的疾病负担在我国尚未知,也未得到足够的重视。为此,本专家共识在儿童GAS疾病诊断、治疗和预防方面进行了全面阐述,涵盖了呼吸病学、感染病学、免疫学、微生物学、心脏病学、肾脏病学、重症医学和预防医学的相关方面,旨在改善中国儿童GAS疾病的管理策略。Group A Streptococcus(GAS)is a very important pathogen,especially for children.On a global scale,GAS is an important cause of morbidity and mortality.But the burden of disease caused by GAS is still unknown in China and also has not obtained enough attention.For this purpose,the expert consensus is comprehensively described in diagnosis,treatment and prevention of GAS diseases in children,covering related aspects of pneumology,infectiology,immunology,microbiology,cardiology,nephrology,critical care medicine and preventive medicine.Accordingly,the consensus document was intended to improve management strategies of GAS disease in Chinese children.

关 键 词：A族链球菌 诊断 治疗 预防 

分 类 号：R725.1[医药卫生—儿科]