古代经典名方温经汤的处方来源与关键信息考证  

Textual Research on the Ancient Classical Prescription Wenjing Decoction(温经汤)

作　　者：陈平 曾瑾[1] 杨安东[1] 张美[1] 尹竹君 戴瑛[1] 李莉[1] 赵军宁[1] 周厚成 周翔 周维 Chen Ping;Zeng Jin;Yang Andong;Zhang Mei;Yin Zhujun;Dai Ying;Li Li;Zhao Junning;Zhou Houcheng;Zhou Xiang;Zhou Wei(Institute of Translational Pharmacology and Clinical Application,Sichuan Academy of Chinese Medicine Sciences,Sichuan Institute for Translational Chinese Medicine,Sichuan Key Laboratory of Translational Chinese Medicine,Sichuan Engineering Technology Research Center for Formation Principle and Quality Evaluation of Genuine Medicinal Materials,Sichuan Engineering Technology Research Center for System Development of Genuine Medicinal Materials,Key Laboratory of Biological Evaluation of Quality of Traditional Chinese Medicine,National Administration of Traditional Chinese Medicine,Chengdu 610041;New Green Medicine Pharmaceutical Co.Ltd.,Chengdu 610031)

机构地区：[1]四川省中医药科学院转化药理与临床应用研究所,四川省中医药转化医学中心,中医药转化医学四川省重点实验室,四川省道地药材形成原理与品质评价工程研究中心,四川省道地药材系统开发工程技术研究中心,国家中医药管理局中药质量生物评价重点研究室,成都610041 [2]四川新绿色药业科技发展有限公司,成都610031

出　　处：《中药药理与临床》2022年第5期187-195,共9页Pharmacology and Clinics of Chinese Materia Medica

基　　金：四川省杰出青年科技人才项目(编号:2020JDJQ0063);四川省科技计划重点研发项目(编号:2020YFS0566)。

摘　　要：根据整理和考证相关医学典籍,从方剂来源、历史沿革、药材的基原和炮制、度量衡的考证、大小温经汤的异同及现在临床应用等方面进行梳理,对比2020年10月15日国家中医药管理局发布的《古代经典名方关键信息表(7首方剂)》温经汤的关键信息,进一步确认温经汤相关技术指标。《妇人良方大全》所载温经汤,所用药味9味,分别考证其基原为:当归(Angelica sinensis(Oliv.)Diels)、川芎(Ligusticum chuanxiong Hort.)、白芍(Paeonia lactiflora Pall.)、肉桂(Cinnamomum cassia Presl.)、牡丹皮(Paeonia suffruticosa Andr.)、莪术(C.kwangsiensis S.G.Lee et C.F.Liang)、人参(Panax ginseng C.A.Mey.)、甘草(Glycyrrhiza uralensis Fisch.)、牛膝(Achyranthes bidentata Bl.)。根据度量衡考证可知处方各药味用量:莪术、当归、白芍、肉桂、牡丹皮、川芎各20.65 g,甘草、人参、牛膝各41.30 g;煎煮服用方法为各药味粉碎后(2 mm~6 mm),每服药20 g左右,加水350 mL,煎煮至280 mL,过滤后温服。按一日一服,则一次处方可服用约12 d。各药味日服量为:当归1.72 g,川芎1.72 g,白芍1.72 g,肉桂1.72 g,牡丹皮1.72 g,莪术1.72 g,人参3.44 g,甘草3.44 g,牛膝3.44 g。其中,莪术基原、当归与牛膝的炮制、煎煮水量、日服剂量等方面与《古代经典名方关键信息表》温经汤不尽一致,该考证结果可供温经汤的开发研究提供参考。According to relevant medical classics,this paper sorted out the sources of Wenjing Decoction(温经汤),the historical evolution,the origins and processing of the medicinal materials,the weights and measures,similarities and differences of Dawenjing Decoction(大温经汤)and Xiaowenjing Decoction(小温经汤),and the current clinical application.Through the comparison with the core information of Wenjing Decoction in Key Information Table of Ancient Classical Famous Formulas(7 Formulas)released by the National Administration of Traditional Chinese Medicine on October 15,2020,relevant technical indicators of Wenjing Decoction were further confirmed.The origins of the 9 medicinals in Wenjing Decoction in A Complete Collection of Effective Prescriptions for Women were confirmed as follows:Angelica sinensis(Oliv.)Diels for Danggui(当归),Ligusticum chuanxiong Hort.for Chuanxiong(川芎),Paeonia lactiflora Pall.for Baishao(白芍),Cinnamomum Cassia Presl.for Rougui(肉桂),Paeonia suffruticosa Andr.for Mudanpi(牡丹皮),Curcuma kwangsiensis S.G.Lee et C.F.Liang for Ezhu(莪术),Panax ginseng C.A.Mey.for Renshen(人参),Glycyrrhiza uralensis Fisch.for Gancao(甘草),and Achyranthes bidentata Bl.Niuxi(牛膝).According to the textual research of weights and measures,20.65 g Ezhu,20.65 g Danggui,20.65 g Baishao,20.65 g Rougui,20.65 g Mudanpi,20.65 g Chuanxiong,41.30 g Gancao,41.30 g Renshen,and 41.30 g Niuxi were used in the prescription.The decocting method should be as follows.The medicinals are grounded(2 mm~6 mm),and 20 g powder was used for each prescription.Then the powder is mixed with 350 mL water,followed by boiling to 280 mL.The yielded mixture is filtrated,and the filtrate is taken warm after filtering.One prescription can be taken for about 12 days,once per day.The daily dosage is 1.72 g Ezhu,1.72 g Danggui,1.72 g Baishao,1.72 g Rougui,1.72 g Mudanpi,1.72 g Chuanxiong,3.44 g Gancao,3.44 g Renshen,and 3.44 g Niuxi,respectively.The origin of Ezhu,processing of Danggui and Niuxi,water added for decoction,an

关 键 词：经典名方 温经汤 妇人大全良方 处方考证 

分 类 号：R289.5[医药卫生—方剂学]