胆管癌患者光动力治疗避光管理的最佳证据总结  

Best Evidence Summary for Light Avoidance Management of Photodynamic Therapy in Patients with Cholangiocarcinoma

作　　者：林穗仪 何家欣 纪翠红[1] 郑思娣 潘靖达 徐晓艳[3] 吴雪莲[4] 凌冬兰 LIN Sui-yi;HE jia-xin;JI Cui-hong;ZHENG Si-di;PAN Jing-da;XU Xiao-yan;WU Xue-lian;LING Dong-lan(Dept.of Hepatobiliary Surgery,the Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,China;Dept.of Breast Surgery,the Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,China;Dept.of Nursing Administration,the Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,China;Dept.of Surgery,the Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,China;College of Nursing,the Hong Kong Polytechnic University,Hong Kong 0000,China)

机构地区：[1]广州医科大学附属第二医院肝胆外科一区,广东广州510260 [2]广州医科大学附属第二医院乳腺外科,广东广州510260 [3]广州医科大学附属第二医院护理部,广东广州510260 [4]广州医科大学附属第二医院外科,广东广州510260 [5]香港理工大学护理学院,中国香港0000

出　　处：《护理学报》2022年第23期39-44,共6页Journal of Nursing（China）

基　　金：2022年国家自然科学基金面上项目(82273087);2019年湖北陈孝平科技发展基金会(CXPJJH11900001-2019205);2020年度广州医科大学临床护理重点专科(B202004)。

摘　　要：目的总结胆管癌患者光动力治疗避光管理的最佳证据,为临床护理工作提供证据支持。方法用PICO模式构建循证问题,按照“6S”证据金字塔系统检索建库至2022年8月在指南网站、数据库、专业协会网站中发表的关于行光动力治疗的胆管癌患者避光管理的文献。由2名研究人员独立进行文献质量评价、证据提取与综合。结果共纳入文献12篇,包括临床决策2篇,指南4篇,专家共识1篇,系统评价2篇,随机对照试验2篇、队列研究1篇。共提取光动力治疗胆管癌的用药适应证和禁忌证、光敏剂用药护理、避光方法、并发症管理、饮食指导、心理护理、健康教育7个维度28条最佳证据。结论本研究为临床医护人员对行光动力治疗的患者进行规范化管理提供了循证依据,建议在评估机构环境及利益相关者的意愿后选择性应用最佳证据,以保证患者安全。Objective To summarize the best evidence on light avoidance management of photodynamic therapy(PDT)in patients with cholangiocarcinoma,and to provide reference for clinical practice.Methods Literature on light avoidance management of PDT in patients with cholangiocarcinoma was searched according to the 6S hierarchy of evidence-based resources in guideline websites,database and related professional association websites from the inception to August 2022.Two researchers evaluated the quality of the included literature,extracted and integrated the evidence.Results Twelve articles were found,including 2 clinical decisions,4guidelines,1 expert consensus,2 systematic reviews,2 randomized controlled trials,and 1 cohort study.Twenty-eight pieces of best evidence were integrated into 7 dimensions,including indications and contraindications for cholangiocarcinoma patients undergoing PDT,nursing care of photosensitizer administration,light-proof methods,complication management,dietary guidance,psychological care,and health education.Conclusion This study contributes to providing evidence-based standardized management in patients undergoing PDT for healthcare providers.It is suggested the best evidence should be applied after environment assessment and willingness of participants,thus to ensure patient safety.

关 键 词：胆管癌患者 光动力疗法 避光 光敏反应 循证护理 

分 类 号：R473.57[医药卫生—护理学]