难治性高血压危险因素与中医体质的特点研究  

Research on Risk Factors and Traditional Chinese Medicine Constitution Features of Resistant Hypertension

作　　者：何焯根 HE Zhuo-Gen(The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120 Guangdong,China)

机构地区：[1]广州中医药大学第二附属医院,广东广州510120

出　　处：《广州中医药大学学报》2022年第11期2491-2495,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(编号:20191164)。

摘　　要：【目的】探讨难治性高血压(RH)患者相关危险因素与中医体质特点,为临床应用中医体质防控RH提供依据。【方法】选取RH和非难治性高血压(NRH)患者各117例及健康体检人群133例,分别作为RH组、NRH组和健康对照组,采用《中医体质分类与判定》标准判定体质类型,分析RH患者的性别、年龄、吸烟史、体质量指数(BMI)、血糖、血脂、血压控制水平等因素与中医体质的关系。【结果】(1)RH患者最常见中医体质类型为气虚质、痰湿质、血瘀质,最常见的体质兼夹类型为3种偏颇体质兼夹、4种偏颇体质兼夹以及2种偏颇体质兼夹,与健康对照组比较,差异有统计学意义(P<0.05),与NRH组比较,差异无统计学意义(P>0.05)。(2)RH组男性患者占比、平均收缩压高于NRH组,差异有统计学意义(P<0.05),而其他危险因素比较,差异无统计学意义(P>0.05)。(3)RH组患者3种常见体质类型的男性比例高于NRH组,气虚质、痰湿质的吸烟史比例、平均收缩压高于NRH组,痰湿质的平均高密度脂蛋白胆固醇(HDL-C)低于NRH组,差异均有统计学意义(P<0.05);血瘀质除性别组成外,其他危险因素与NRH组比较,差异均无统计学意义(P>0.05)。【结论】气虚质、痰湿质、血瘀质是RH患者最常见中医体质类型,其中气虚质和痰湿质患者要注意戒烟及控制收缩压,痰湿质患者仍需注意HDL-C的管理。Objective To investigate the risk factors and the characteristics of traditional Chinese medicine(TCM)constitution of patients with resistant hypertension(RH),and to provide a basis for the clinical prevention and control of RH based on the TCM constitution.Methods One hundred and seventeen patients with RH,117 cases of non-resistant hypertension(NRH)and 133 cases of healthy control from the healthy physical examination population were selected as the RH group,the NRH group and the healthy control group respectively.Traditional Chinese Medicine Constitution Classification and Distinguishing Scale was used for the identification of the TCM constitution type,and then the correlation of TCM constitution type with the risk factors of gender,age,smoking history,body mass index(BMI),blood glucose,blood lipid,and blood pressure control level of RH patients was explored.Results(1)The most common TCM constitution types of RH patients were qi deficiency constitution,phlegm-damp constitution and blood stasis constitution,and the most common types of complicated constitutions were the complicated constitution of 3 biased constitution types,the complicated constitution of4 biased constitution types,and the complicated constitution of 2 biased constitution types.The differences in the TCM constitution types and the complicated constitution types of RH group were statistically significant in comparison with the healthy control group(P<0.05),while the differences were not statistically significant compared with the NRH group(P>0.05).(2)The percentage of male patients and mean systolic blood pressure in the RH group were higher than those in the NRH group,and the differences were statistically significant(P<0.05),while the differences of other risk factors were not statistically significant between RH group and NRH group(P>0.05).(3)In the RH group,the proportion of males with the three common constitution types was higher than that in the NRH group.The proportion of patients with a history of smoking and the mean systolic blood p

关 键 词：难治性高血压 危险因素 中医体质 气虚质 痰湿质 血瘀质 血压 血脂 

分 类 号：R259.441[医药卫生—中西医结合]