Double-Stranded DNA Matrix for Photosensitization Switching  

作　　者：Yanying Wang Hao Hu Tianyu Dong Hayam Mansour Xinfeng Zhang Feng Li Peng Wu 

机构地区：[1]Key Laboratory of Green Chemistry and Technology,Ministry of Education,College of Chemistry,Sichuan University,Chengdu 610064 [2]Analytical and Testing Center,Sichuan University,Chengdu 610064 [3]Department of Chemistry,Brock University,St.Catharines,ON L2S 3A1 [4]Department of Cell Biology,National Research Centre,Cairo 12622 [5]College of Materials and Chemistry&Chemical Engineering,Chengdu University of Technology,Chengdu 610059

出　　处：《CCS Chemistry》2021年第9期2394-2404,共11页中国化学会会刊（英文）

基　　金：support from the National Natural Science Foundation of China(nos.21874093 and 21522505);the Fundamental Research Funds for the Central China Universities(no.2018SCUH0075).

摘　　要：Photosensitization,originated from the activation of triplet states,is the basis of many photodynamic applications,but often competes with a series of nonradiative processes.Herein,we communicate a new function of double-stranded DNA(dsDNA)for label-free photosensitization switching.Up to∼70-fold singlet oxygen generation boosting was observed for SYBR Green I(SG)upon binding with dsDNA.Detailed photophysical and theoretical studies have revealed the role of dsDNA as a matrix,which could efficiently suppress the nonradiative transitions of SG.

关 键 词：PHOTOSENSITIZATION DNA singlet oxygen nucleic acid testing SYBR Green I 

分 类 号：O43[机械工程—光学工程]