A Water-Soluble Photothermal Host–Guest Complex with pH-Sensitive Superlarge Redshift Absorption  

作　　者：Xiao-Qi Xu Hongguang Liao Haocheng Liu Yanji Chu Yonglin He Yapei Wang 

机构地区：[1]Department of Chemistry,Renmin University of China,Beijing 100872

出　　处：《CCS Chemistry》2021年第10期2520-2529,共10页中国化学会会刊（英文）

基　　金：supported by the National Natural Science Foundation of China(nos.21825503 and 21674127).

摘　　要：Near infrared(NIR)absorbers for photothermal therapy are arousing great attention in tumor diagnosis and ablation.However,the inevitably wide distribution of NIR absorbers generally causes equal photothermal injuries to tumor tissues and healthy tissues.An initiative targeting strategy based on pH-sensitive redshift absorption has been proposed for NIR-induced hyperthermia only in tumor tissue.In this work,we develop a NIR absorber with superlarge redshift from the middle visible light region to NIR light region once the pH value drops.

关 键 词：photothermal conversion pH-sensitive abs orption host-guest interaction WATER-SOLUBILITY aniline trimer 

分 类 号：R318[医药卫生—生物医学工程] R730.5[医药卫生—基础医学]