碳酸钙纳米给药系统在肿瘤治疗中的应用  

Application of calcium carbonate based nano drug deliverysystem in cancer therapy

作　　者：邱琳[1] 王程 崔朋飞 周舒文[1] 胡华安子 蒋鹏举[1] 王建浩[1] QIU Lin;WANG Cheng;CUI Pengfei;ZHOU Shuwen;HU Huaanzi;JIANG Pengju;WANG Jianhao(School of Pharmacy,Changzhou University,Changzhou 213164,China)

机构地区：[1]常州大学药学院,江苏常州213164

出　　处：《常州大学学报（自然科学版）》2023年第1期78-85,共8页Journal of Changzhou University：Natural Science Edition

基　　金：江苏省重点研发计划资助项目(BE2018639);常州大学2020年科研启动资助基金(ZMF20020455)。

摘　　要：碳酸钙具有成本低廉、毒副作用低等优点,在构建纳米给药系统中具有极大的优势。文章围绕肿瘤治疗的应用需求,分别从碳酸钙纳米粒的优势、碳酸钙纳米粒的制备和递送不同类型肿瘤药物的碳酸钙纳米给药系统等3个方面进行综述,总结了纳米给药系统面临的困境和未来的研究方向。Calcium carbonate has great advantages in the construction of nano drug delivery systems due to its low cost and high biocompatibility.In this review,focusing on the requirements in cancer therapy,the advantages of calcium carbonate nanoparticles,the preparation of carbonate nanoparticles,and calcium carbonate nanoparticle-based nano drug delivery systems for the delivery of different types of cancer drugs were reviewed.The challenges of this system and future research directions were also summarized.

关 键 词：碳酸钙 纳米给药系统 肿瘤治疗 

分 类 号：TK8[动力工程及工程热物理—流体机械及工程]