液体敷料在早产儿双相气道正压通气鼻损伤中的应用  

Application of liquid dressing in the treatment of bi-level positive airway pressure nasal injury in premature infants

作　　者：谢瑛玲 刘素佳 林云峰 XIE Yingling;LIU Sujia;LIN Yunfeng(Department of Neonatology,Fujian Maternity and Child Health Hospital,Fujian Province,Fuzhou350001,China;Department of Neonatology,Fujian Children's Hospital,Fujian Province,Fuzhou350001,China)

机构地区：[1]福建省妇幼保健院新生儿科,福建福州350001 [2]福建省儿童医院新生儿科,福建福州350001

出　　处：《中国当代医药》2022年第36期100-102,106,共4页China Modern Medicine

基　　金：福建省卫健委科技计划项目(2020QNA026)。

摘　　要：目的 探讨液体敷料在早产儿双相气道正压通气(BiPAP)鼻损伤中的应用。方法 回顾性选取2019年1月至2021年12月福建省妇幼保健院新生儿科收治的230例接受BiPAP治疗超过4 h的早产儿作为研究对象,按照是否使用液体敷料分为干预组(有使用液体敷料,107例)与对照组(未使用液体敷料,123例),两组均观察75 d。采用澳大利亚皇家妇女医院(RWH)鼻腔完整性和压力图评估患儿住院期间鼻损伤的情况,鼻损伤分期从0期(无破损)到4期(广泛破损)。比较两组患儿鼻部损伤的严重程度及并发症发生情况。结果 干预组鼻部损伤的严重程度轻于对照组,差异有统计学意义(P<0.05)。两组的并发症总发生率比较,差异无统计学意义(P>0.05)。结论液体敷料可以有效降低接受BiPAP早产儿鼻损伤的严重程度。Objective To investigate the application of liquid dressing in bi-level positive airway pressure ventilation(BiPAP) nasal injury in preterm infants. Methods A total of 230 preterm infants who received BiPAP treatment for more than4 hours from January 2019 to December 2021 in the Department of Neonatology, Fujian Maternity and Child Health Hospital were retrospectively selected as the research objects. According to whether liquid dressing was used, they were divided into the intervention group(107 cases with liquid dressing) and the control group(123 cases without liquid dressing). Both groups were observed for 75 days. Nasal Integrity and Pressure Chart from the Royal Australian Women’s Hospital(RWH) were used to assess nasal injuries during hospitalization. Nasal injury stages from stage 0(no damage) to stage 4(extensive damage). The severity of nasal injury and the incidence of adverse events were compared between the two groups. Results The severity of nasal injury in the intervention group was less severe than that in the control group, and the difference was statistically significant(P<0.05). There was no significant difference in the total incidence of adverse events between the two groups(P>0.05). Conclusion Liquid dressing can effectively reduce the severity of nasal injury in premature infants receiving Bi PAP.

关 键 词：液体敷料 早产儿 双相气道正压通气 鼻损伤 

分 类 号：R722.6[医药卫生—儿科]