复方巴戟天健骨颗粒的水提工艺优化研究  

Optimization of Water Extraction Process of Compound BaJiTian JianGu Granules

作　　者：龚燕珍 严锦贤[2] 倪立坚[2] 李颖[2] 王和鸣[3] GONG Yang-zheng;YAN Jin-xian;NI Li-jian;LI Ying;WANG He-ming(Guangze County Hospital,Guangze 354199,China;The Second People’s Hospital of Fujian Province,Fuzhou 350003,China;Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China)

机构地区：[1]光泽县医院,福建光泽354100 [2]福建中医药大学附属第二人民医院,福建福州350003 [3]福建中医药大学,福建福州350122

出　　处：《海峡药学》2022年第12期4-6,共3页Strait Pharmaceutical Journal

基　　金：福建省医疗机构中药制剂重点实验室(福建中医药大学)。

摘　　要：目的优化复方巴戟天健骨颗粒的水提工艺。方法单因素考察溶媒使用量;以丹酚酸B等三种有效成份含量和干浸膏率的加权评分为综合指标,正交试验研究复方巴戟天健骨颗粒的水提工艺,并进行工艺验证。结果最佳工艺为药材浸泡60 min,10倍水提取3次,每次60 min。结论水提工艺合理、可靠、可行。OBJECTIVE Optimization of Water Extraction Process of Fufangbajitian Jiangu Granules.METHODS With the comprehensive score of baicalin and dry extract rate as the evaluation index,the water estraction process of Compound BaJiTian JianGu Granules was optimi 2 ed by orthogonal test,and the reliability of the optimal process was verftied.RESULTS The best preparation process was as follow:The medicinal materials were soaked for 60 min,extracted 3 times with 10 times of extraction solvent,60 min each time.CONCLUSIONS The optimized centrifugal process of water extraction is reasonable,stable and reliable.

关 键 词：复方巴戟天健骨颗粒 丹酚酸B 川续断皂苷Ⅵ 淫羊藿苷 正交设计试验 

分 类 号：R94[医药卫生—药剂学]