某市新型冠状病毒肺炎疫情期间孕妇焦虑抑郁对妊娠结局的影响  

Effects of anxiety and depression on pregnancy outcomes in pregnant women during COVID-19 outbreak in a city

作　　者：陈奕铭[1] 杨丽萍[2] 王燕侠[3] 张春花[3] 陈丽娜 金玉霞 常旭红[4] 毛宝宏[3] Chen Yiming;Yang Liping;Wang Yanxia;Zhang Chunhua;Chen Lina;Jin Yuxia;Chang Xuhong;Mao Baohong(Department of Operation Management,Gansu Provincial Maternal and Child Health Hospital;Department of Public Health and Hospital Infection Management of Gansu Provincial Hospital of Traditional Chinese Medicine;Gansu Maternal and Child Health Hospital Research Center;School of Public Health,Lanzhou University,Lanzhou Gansu 730050,P.R.China)

机构地区：[1]甘肃省妇幼保健院运营管理部,甘肃兰州730050 [2]甘肃省中医院公共卫生与医院感染管理处 [3]甘肃省妇幼保健院科研中心 [4]兰州大学公共卫生学院

出　　处：《中国计划生育和妇产科》2022年第12期27-31,共5页Chinese Journal of Family Planning & Gynecotokology

基　　金：陇原青年创新创业人才项目(项目编号:2021LQTD10);兰州市新冠肺炎防控技术研究项目(项目编号:2020-XG-12)。

摘　　要：目的分析新型冠状病毒肺炎疫情期间孕妇焦虑抑郁对异常妊娠结局的影响,为控制异常妊娠结局的发生提供科学依据。方法选取2021年10~12月在甘肃省妇幼保健院进行孕期检查并分娩的1671例孕妇为研究对象,通过问卷调查孕妇焦虑、抑郁状况并收集妊娠相关资料,采用χ^(2)检验及Logistic回归模型分析孕妇焦虑抑郁对妊娠结局的影响。结果孕妇的年龄、住址、文化程度、月收入和产检次数等因素均会影响早产、低出生体重、剖宫产和妊娠合并症发生率,差异有统计学意义(P<0.05)。同时存在焦虑抑郁的孕妇异常妊娠结局发生率高于只存在单一焦虑或抑郁的孕妇(P<0.05)。通过Logistic回归控制单因素分析有意义的变量后,焦虑合并抑郁是早产(OR=1.733,1.048-2.868)、低出生体重(OR=2.429,1.315-4.486)和剖宫产分娩(OR=1.483,1.012-2.174)的危险因素,差异有统计学意义(P<0.05)。结论新型冠状病毒肺炎疫情期间,孕妇焦虑抑郁的发生率增高,影响早产和低出生体重婴儿发生率。Objective To clarify the effect of anxiety and depression of pregnant women on abnormal pregnancy outcomes during COVID-19 epidemic,and to provide scientific basis for controlling the occurrence of abnormal pregnancy outcomes.Methods 1671 pregnant women who examined during pregnancy and delivered in Gansu Maternal and Child Health Hospital from October 2021 to December 2021 were selected as subjects.Questionnaire survey on anxiety,depression of pregnant women and collection of pregnancy-related data and the effects of anxiety and depression on pregnancy outcomes was analyzed byχ^(2)test and Logistic regression model.Results The age,address,education level,monthly income and number of prenatal examinations of pregnant women affected the incidence of preterm birth,low birth weight,cesarean section and pregnancy complications,and the difference was statistically significant(P<0.05).The incidence of abnormal pregnancy outcome in pregnant women with anxiety and depression was higher than that in pregnant women with single anxiety or depression(P<0.05).After controlling for significant variables by Logistic regression analysis,anxiety combined with depression was risk factor for preterm birth(OR=1.733,1.048-2.868),low birth weight(OR=2.429,1.315-4.486)and caesarean delivery(OR=1.483,1.012-2.174),the difference was statistically significant(P<0.05).Conclusion During the COVID-19 epidemic,the incidence of anxiety and depression in pregnant women has increased,and maternal depression and anxiety affect the incidence of preterm birth and low-birth-weight babies.

关 键 词：新型冠状病毒肺炎疫情 孕妇 焦虑 抑郁 妊娠结局 

分 类 号：R473.71[医药卫生—护理学]