个性化医学营养治疗对妊娠期甲状腺疾病合并妊娠期糖尿病的应用效果  

Application Effect of Individualized Medicine Nutrition Therapy on Gestational Thyroid Disease Complicated with Gestational Diabetes Mellitus

作　　者：杨毅 马良坤[2] 孙崟[2] 李莉 许娟[3] 宁锋 Yang Yi;Ma Liang-kun;Sun Yin;Li Li;Xu Juan;Ning Feng(Fengtai District Maternal and Child Health Care Hospital,Beijing 100069,China;Peking Union Hospital,Beijing 100730,China;Fengtai District Dahongmen Community Health Service Center,Beijing 100075,China)

机构地区：[1]北京丰台区妇幼保健院,北京100069 [2]北京协和医院,北京100730 [3]北京市丰台区大红门社区卫生服务中心,北京100075

出　　处：《中外医药研究》2022年第10期3-5,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：中国医学科学院医学与健康科技创新工程项目(编号:2021-I2M-1-023)。

摘　　要：目的:分析个性化医学营养治疗(IMNT)对妊娠期甲状腺疾病合并妊娠糖尿病(GDM)孕妇的应用效果。方法:选取2019年1月-2021年6月北京丰台区妇幼保健院收治的妊娠期甲状腺疾病合并GDM孕妇109例为观察对象,根据随机数字表法分为观察组55例和对照组54例,观察组行IMNT,对照组行常规营养宣教,比较两组孕期体重增长、血糖水平、妊娠结局、新生儿情况。结果:观察组孕期体重增加高于对照组,差异有统计学意义(P<0.05)。治疗后,两组孕妇空腹血糖(FPG)、餐后2 h血糖水平均下降,观察组低于对照组,观察组FPG下降幅度大于对照组,差异有统计学意义(P<0.05)。观察组正常分娩率优于对照组,羊水过少(多)发生率、高血压发生率、产褥期贫血发生率低于对照组,差异有统计学意义(P<0.05)。观察组正常新生儿比例高于对照组,差异有统计学意义(P<0.05);观察组巨大儿发生率和胎儿宫内窘迫低于对照组,差异有统计学意义(P<0.05)。结论:IMNT可控制孕妇孕期血糖和体重,减少妊娠期并发症,改善妊娠结局。Objective:To analyze the effect of individualized medicine nutrition therapy(IMNT)on pregnant women with gestational thyroid disease complicated with gestational diabetes mellitus(GDM).Methods:A total of 109 pregnant women with thyroid disease during pregnancy complicated with GDM admitted to Fengtai District Maternal and Child Health Care Hospital from January 2019 to June 2021 were selected as the observation objects,and were divided into observation group(55 cases)and control group(54 cases)according to random number table method.The observation group received IMNT and the control group received conventional nutrition education.Pregnancy weight gain,blood glucose level,pregnancy outcome and neonatal situation were compared between the two groups.Results:The weight gain during pregnancy in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,fasting blood glucose(FPG)and 2 h postprandial blood glucose levels of pregnant women in both groups were decreased,the observation group was lower than the control group,the FBG of the observation group was greater than the control group,the difference was statistically significant(P<0.05).The normal delivery rate of the observation group was better than that of the control group,and the incidence of oligohydramnios,hypertension and puerperal anemia was lower than that of the control group,with statistical significance(P<0.05).The proportion of normal newborns in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The incidence of macrosomia and fetal distress in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:IMNT can control pregnant women's blood glucose and weight during pregnancy,reduce pregnancy complications and improve pregnancy outcome.

关 键 词：个性化医学营养治疗 妊娠期甲状腺疾病 妊娠期糖尿病 血糖 妊娠结局 

分 类 号：R71[医药卫生—妇产科学]