卫矛科三种中药治疗类风湿关节炎作用机制的研究概况  

Research Overview on the Mechanism of Three Chinese Medicines of Celastraceae in the Treatment of Rheumatoid Arthritis

作　　者：赵连宇 陈玲 莫华兰 王航飞 戴小良 ZHAO Lianyu;CHEN Ling;MO Hualan;WANG Hangfei;DAI Xiaoliang(Department of Rheumatology,Guilin TCM Hospital,Guilin 541000,China)

机构地区：[1]桂林市中医医院风湿病科,广西桂林541000

出　　处：《中国民族民间医药》2022年第20期49-54,共6页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：广西壮族自治区中医药管理局科研课题(编号:GZZC2020299);国家中医药管理局第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]1号)。

摘　　要：随着中医药事业的发展,很多治疗类风湿关节炎有效的中药被发掘出来,并且已经在临床上得到了广泛应用。其中在临床应用最广泛的是卫矛科雷公藤属中药雷公藤、昆明山海棠以及卫矛科南蛇藤属植物南蛇藤。文章回顾了近十年对这些中药治疗类风湿关节炎的作用机制的研究,得出这些药物中主要的抗风湿成分及其治疗类风湿关节炎的作用机制。为这些中药临床治疗类风湿关节炎提供理论依据,也为这些有效成分相关药物的开发提供合理的参考依据。With the development of traditional Chinese medicine,many effective traditional Chinese medicines for the treatment of rheumatoid arthritis have been discovered and have been widely used in clinical practice.Among them,the most widely used in clinical applications areTripterygium wilfordiiHook.f.,Tripterygium hypoglaucum(Levl.)Hutch andCelastrus orbiculatusThunb.The article reviewed the research on the mechanism of these traditional Chinese medicines in the treatment of rheumatoid arthritis in the past ten years,and concluded that the main anti-rheumatic components in these traditional Chinese medicines and their mechanism of action in the treatment of rheumatoid arthritis.It provides a theoretical basis for the clinical treatment of rheumatoid arthritis with these traditional Chinese medicines,and also provides a reasonable reference for the development of these active ingredients-related drugs.

关 键 词：雷公藤 昆明山海棠 南蛇藤 雷公藤甲素 雷公藤红素 南蛇藤素 

分 类 号：R255.6[医药卫生—中医内科学]