桑属植物中异戊烯基黄酮类化合物及其药理活性研究进展  

Research progress on prenylated flavonoids from Morus plants and their pharmacological activities

作　　者：姜玥 刘洋洋 田海涛 邓志鹏 JIANG Yue;LIU Yang-yang;TIAN Hai-tao;DENG Zhi-peng(School of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]山东中医药大学药学院,山东济南250355

出　　处：《中草药》2022年第21期6948-6958,共11页Chinese Traditional and Herbal Drugs

基　　金：山东省自然科学基金资助项目(ZR2019MH051);山东省自然科学基金资助项目(ZR2021QC080)。

摘　　要：桑科桑属植物在我国分布广泛,其枝、叶、根皮、果实均可入药,具有很高的药用价值。目前从桑属植物中分离得到的化学成分有黄酮、生物碱、香豆素、萜类、多糖等,其中异戊烯基黄酮类化合物为其特征成分,具有抗菌、抗炎、抗肿瘤、抗病毒、降血压、降血糖、抗氧化等多种药理活性。主要对桑属植物中异戊烯基黄酮类化合物及其药理活性的研究进展进行综述,为桑属植物的开发利用和药效物质研究提供参考。Morus plants in Moraceae family are widely distributed in our country with high value for the medicinal uses of their branches,leaves,root bark,and fruits.At present,chemical constituents isolated from Morus plants mainly are flavonoids,alkaloids,coumarins,terpenes,polysaccharides,etc.Among them,prenylated flavonoids are the characteristic components in Morus plants with multiple pharmacological properties,such as antibacterial,anti-inflammatory,antitumor,antiviral,hypotensive,hypoglycemic and antioxidant activities.In this paper,research progress on prenylated flavonoids from Morus plants and their pharmacological activities was reviewed,in order to provide references for development and medicinal substances of Morus plants.

关 键 词：桑属 异戊烯基黄酮 抗菌 抗炎 抗肿瘤 抗病毒 

分 类 号：R282.710.5[医药卫生—中药学]