经腹超声联合超声造影评估胰腺癌临床分期的价值研究  

Study on the value of transabdominal ultrasound combined with contrast-enhanced ultrasound in assessing the clinical staging of pancreatic cancer

作　　者：段丽红 郭丽苹[1] 尹丽[1] 杨爽[1] 赵之 王福玲 DUAN Li-hong;GUO Li-ping;YIN Li(Department of Ultrasound,Zhongshan Hospital Affiliated to Dalian University,Dalian 116000,China)

机构地区：[1]大连大学附属中山医院超声科,116000

出　　处：《中国现代药物应用》2023年第1期63-66,共4页Chinese Journal of Modern Drug Application

摘　　要：目的分析经腹部超声检查(经腹超声)联合超声造影评估胰腺癌临床分期的价值。方法回顾性分析115例胰腺癌患者的临床资料,所有患者入院时均行经腹超声、超声造影检查,并以穿刺活检病理学检查结果为“金标准”,依据相关指南评估胰腺癌分期情况,分析经腹超声联合超声造影评估胰腺癌临床分期的价值。结果115例胰腺癌患者中,0期8例,Ⅰ期19例,Ⅱ期26例,Ⅲ期39例,Ⅳ期23例。经Kappa一致性检验,经腹超声、超声造影单独诊断胰腺癌临床分期和穿刺活检病理学检查结果的一致性一般(Kappa=0.677、0.747,P<0.01);经腹超声联合超声造影诊断胰腺癌临床分期和穿刺活检病理学检查结果一致性较好(Kappa=0.897,P<0.01)。经腹超声联合超声造影诊断胰腺癌临床分期的准确率为92.17%(106/115),高于经腹超声、超声造影单独诊断胰腺癌临床分期的75.65%(87/115)、80.87%(93/115),差异有统计学意义(χ2=11.627、6.301,P<0.05);经腹超声与超声造影诊断胰腺癌临床分期的准确率比较,差异无统计学意义(χ2=0.920,P>0.05)。结论经腹超声联合超声造影对胰腺癌临床分期的评估价值较高。Objective To analyze the value of transabdominal ultrasound combined with contrastenhanced ultrasound in assessing the clinical staging of pancreatic cancer. Methods The clinical data of 115 pancreatic cancer patients were retrospectively analyzed. All patients underwent transabdominal ultrasound and contrast-enhanced ultrasound on admission, and the staging of pancreatic cancer was evaluated according to the relevant guidelines using the pathological findings of puncture biopsy as the "gold standard", and the value of transabdominal ultrasound combined with contrast-enhanced ultrasound in assessing the clinical staging of pancreatic cancer was analyzed. Results Among 115 patients with pancreatic cancer, 8 cases were in stage 0,19 cases in stage Ⅰ, 26 cases in stage Ⅱ, 39 cases in stage Ⅲ, and 23 cases in stage Ⅳ. Kappa consistency test showed that the consistency of clinical staging and biopsy pathology results by transabdominal ultrasound and contrast-enhanced ultrasound alone in diagnosis of pancreatic cancer was general(Kappa=0.677, 0.747;P<0.01);the clinical staging of pancreatic cancer diagnosed by transabdominal ultrasound combined with contrastenhanced ultrasound was in good consistency with the biopsy pathology results(Kappa=0.897, P<0.01). The accuracy rate of transabdominal ultrasound combined with contrast-enhanced ultrasound in diagnosing clinical staging of pancreatic cancer was 92.17%(106/115), which was higher than 75.65%(87/115) and 80.87%(93/115)of transabdominal ultrasound and contrast-enhanced ultrasound alone, and the difference was statistically significant(χ2=11.627, 6.301;P<0.05). There was no significant difference between transabdominal ultrasound and contrast-enhanced ultrasound in the diagnostic accuracy of clinical staging of pancreatic cancer(χ2=0.920,P>0.05). Conclusion Transabdominal ultrasound combined with contrast-enhanced ultrasound is of high value in the assessment of clinical staging of pancreatic cancer.

关 键 词：胰腺癌 经腹部超声检查 超声造影 临床分期 

分 类 号：R445.1[医药卫生—影像医学与核医学] R735.9[医药卫生—诊断学]