“健脾化浊”推拿法对2型糖尿病患者糖代谢和肠道菌群的影响  

Effect of “Invigorating the Spleen and Transforming the Turbidity” Tuina on Glucose Metabolism and Intestinal Flora in Patients with Type 2 diabetes Mellitus

作　　者：桑佳佳 陶琦[1] 郝锋 熊震坤[1] 胡骏 吴云川[2] SANG Jiajia;Tao Qi;HAO Feng;XIONG Zhenkun;HU Jun;WU Yunchuan(Jiangsu Province Hospital of Chinese Medicine/Affiliated Hospital of Nanjing University of Chinese Medicine,Jiangsu Nanjing 210029,China;School of Acupuncture-Moxibustion and Tuina of Nanjing University of Chinese Medicine,School of Health Preservation and Rehabilitation of Nanjing University of Chinese Medicine,Jiangsu Nanjing 210023,China)

机构地区：[1]江苏省中医院/南京中医药大学附属医院,江苏南京210029 [2]南京中医药大学针灸推拿学院·养生康复学院,江苏南京210023

出　　处：《中医药临床杂志》2023年第1期155-160,共6页Clinical Journal of Traditional Chinese Medicine

基　　金：江苏省中医药管理局江苏省名老中医药专家传承工作室建设项目(2011ZY-67)。

摘　　要：目的:观察“健脾化浊”推拿法对“脾虚浊滞证”2型糖尿病患者糖代谢和肠道菌群的影响。方法:将60例符合纳入标准的受试患者随机分为对照组、常规推拿组与“健脾化浊”推拿组,三组患者均维持受试前降糖药物治疗方案,常规推拿组与“健脾化浊”推拿组各加用不同推拿法干预。治疗8周后观测三组患者的中医疗效、糖代谢值和肠道菌群水平变化。结果:干预后“健脾化浊”推拿组证候积分变化及疗效总有效率明显高于对照组和常规推拿组(P<0.01);对照组糖代谢值治疗前后无统计学差异(P>0.05),“健脾化浊”推拿组和常规推拿组较干预前均明显降低(P<0.01),且二者间比较无统计学差异(P>0.05)。对照组肠道菌群水平治疗前后无统计学差异(P>0.05),“健脾化浊”推拿组较干预前明显改善(P<0.01),常规推拿组中除肠球菌外均具有一定改善(P<0.05)。结论:综合各评价指标,“健脾化浊”推拿法较常规推拿法临床疗效更具优势,在有效减轻患者症状及糖代谢紊乱的同时,可改善体内肠道菌群紊乱。Objective: To observe the effect of“ invigorating spleen and removing turbidity” massage on glucose metabolism and intestinal flora in type 2 diabetic patients with“ spleen deficiency and turbidity stagnation syndrome”. Methods: 60 patients who met the inclusion criteria were randomly divided into the control group, the conventional massage group and the“ invigorating spleen and removing turbidity” massage group. The patients in the three groups maintained the treatment plan of hypoglycemic drugs before the test, and the conventional massage group and the“ The invigorating the spleen and resolving turbidity” massage group was additionally intervened with different massage methods. After 8 weeks of treatment, the TCM curative effect, glucose metabolism value and intestinal flora level changes were observed in the three groups of patients. Results: After the intervention, the change of syndrome scores and the total effective rate of curative effect in the“ invigorating the spleen and removing turbidity” massage group were significantly higher than those in the control group and the conventional massage group(P<0.01);there was no statistical difference in the glucose metabolism value of the control group before and after treatment(P>0.05), the“ invigorating spleen and removing turbidity” massage group and the conventional massage group were significantly lower than those before the intervention(P<0.01), and there was no statistical difference between the two(P>0.05). There was no signifi-cant difference in the level of intestinal flora in the control group before and after treatment(P>0.05), and the“ invigorating spleen and turbidity” massage group was significantly improved compared with before intervention(P<0.01), and the conventional massage group had some improvement except for enterococci(P<0.05). Conclusion: Based on various evaluation indicators, the“ invigorating spleen and removing turbidity” massage method has more advantages in clinical efficacy than conventional massage m

关 键 词：2型糖尿病 “健脾化浊”推拿法 糖代谢 肠道菌群 

分 类 号：R587.1[医药卫生—内分泌]